BACKGROUND Fine needle aspiration biopsy represents the critical initial diagnostic test used for evaluation of thyroid nodules. Our objectives were to determine the cytological distribution, the utility of clinicopathologic characteristics for predicting malignancy and the true proportion of cancer among individuals who presented with indeterminate cytology and had undergone thyroid surgery fo...

We report two cases of follicular adenoma of the thyroid with extensive extracellular mucin deposition. Fine needle aspiration in Case 1 showed singly discohesive polygonal cells in a granular mucinous background. They contained abundant eosinophilic cytoplasm, nuclear irregularities, and frequent nuclear inclusions with occasional bizarre mitoses. A right lobectomy was done. In Case 2, a 47-ye...

Dear Editor, Low-grade fi bromyxoid sarcoma (LGFMS) is a rare form of neoplasm that usually occurs in the deep soft tissue of the lower limbs with a tendency towards local recurrence and distant metastasis. LGFMS affects mainly the young and middle-aged, with both gender having an equal chance of being affected. To the best of our knowledge, there is only 1 case of thyroid LGFMS reported in the...

Medullary thyroid cancer (MTC) is a rare neuroendocrine neoplasm that accounts for approximately 5% of all thyroid malignancies. The natural history of MTC is characterized by early lymph node and distant metastases, making complete surgical cure often impossible. Conventional chemotherapy and external beam radiation have been largely ineffective in altering the natural history of MTC. Therefor...

Adenoid cystic carcinoma is a malignant neoplasm most commonly originating in salivary glands of head and neck region. Its occurrence elsewhere is rare and extension to thyroid even rarer. We report a 27 year old male who was diagnosed to have features of adenoid cystic carcinoma in fine needle aspirate of the thyroid swelling and subsequently confirmed by histopathology. Extensive search faile...

PURPOSE To analyse thyroid carcinomas having an extrathyroid extension in order to identify the principal prognostic factors and outline an effective therapeutic strategy. METHODS We selected a sample of 160 patients suffering from locally advanced "well differentiated thyroid carcinoma (T4) who had undergone surgery at the Department of Surgery of University of Rome "La Sapienza". The sample...

Materials and methods: A retrospective cross-sectional study in which all cases of thyroid nodules, presented to the OPC between September 2009 and August 2015 at King Abdulaziz NGHA. All preoperative cytologic examination by FNA and concurrent postoperative histopathologic examination were included. All FNA diagnoses were reclassified using the thyroid FNA Bethesda reporting system, including ...

It has been well established in the literature that the cribriform-morular variant of papillary thyroid carcinoma (CMVPTC) has been observed with higher frequency in familial adenomatous polyposis (FAP) patients. In the usual setting, patients with FAP are identified based on their germline mutations and the diagnosis of thyroid neoplasm is made after the FAP diagnosis. We herein report a case ...