Abstract Leptin plays a major role in the regulation of energy intake and expenditure, triggering effects on several tissues, such as hypothalamic-pituitary-thyroid axis. The reported leptin thyroid are controversial, being mainly explored during imbalance. Therefore, aim this study was to evaluate function rats fed ad libitum distinguishing direct responses from those mediated by leptin-depend...

salivary gland involvement is one of the radioiodine therapy complications. salivary gland scintigraphy in quantitative mode can accurately evaluate salivary gland function. methods: salivary gland scintigraphy was performed with tc-99m pertechnetate, at the time of iodine therapy as a basic study and then 3 weeks and 3 months afterwards. ejection fraction (ef) of parotid and submandibular glan...

introduction: among the endocrine diseases, hypothyroidism is the commonest after diabetes.thyroid hormones (t3,t4) are essential for genital organs function. apoptosis process in ovarian cells plays a significant role of development in ovarian follicles. the aim of the present study was determine the apoptotic index induced by hypothyroidism in rat ovarian follicles. materials and methods: in ...

HYPOTHESIS The detection of suspected malignant thyroid nodules by ultrasonography is associated with thyroid gland volume and tumor size. DESIGN Prospective clinical trial. SETTING A tertiary referral center. PATIENTS Three hundred sixty-five patients with a multinodular goiter with coexistent dominant nodules. MAIN OUTCOME MEASURES The correlation between thyroid gland volume and tumo...

BACKGROUND Indications for thyroidectomy during laryngectomy are controversial. We examined whether clinicopathologic features can predict thyroid gland involvement, and the prognostic effect of thyroid gland involvement in patients undergoing total laryngectomy. METHODS The study set out to review preoperative assessment, operation findings, pathologic findings, and follow-up data. RESULTS...

Tyrosine kinase inhibitors (TKI) belong to a new class of molecular multitargeted anticancer therapy which targets different growth factor receptors and hence attenuates cancer cell survival and growth. Since their introduction as adjunct treatment for renal cell carcinoma and gastrointestinal stromal tumors (GIST), a number of reports have demonstrated that TKI can induce thyroid dysfunction w...

Introduction: Computed tomography (CT) consists of 11% of all imaging methods, but accounts for approximately 67% of radiation exposure due to diagnostic cases. More than one-third of all CT scans are done in the head and neck area. The thyroid gland is irradiated during CT head and neck. According to studies, this gland has the highest levels of radiation-induced cancer, and i...

Introduction: Thyroid hormones play an important role in the regulation of metabolism, maturity and reproduction. Thyroid dysfunction affects almost all endocrine glands such as pituitary and testis. The aim of this study was to investigate alterations of testosterone and luteinizing hormone (LH) serum levels as well as weights of thyroid gland and testes in methimazole (MMI)-induced hypothy...

metastasis to the oral region is very rare and accounts for less than 1% of oral malignant tumors. breast, lung, kidney, adrenal, gastro intestinal tract and prostates are most common primary tumors from which metastasis to oral region occur frequently. metastasis from thyroid gland is extremely rare to oral region. we present an unusual case of metastatic follicular carcinoma of thyroid in max...