bleomycin (blm)as an anti-cancer agent causes tissue toxicities through dna damaging and cell deaths. the aim of this study was to investigate the effects of thymol against genotoxicity and anti-proliferation induced by blm in normal human lymphocytes and ovarian cancer cells.peripheral blood samples were collected from human volunteers and were incubated with thymolat different concentrations ...

OBJECTIVES To determine the effect of chlorhexidine varnish on the prevention of caries in permanent first molars. METHODS Two groups of 6-7-year-old school children were followed up in a clinical trial, a group of 86 children whose teeth were treated with a chlorhexidine-thymol varnish (Cervitec) and a control group of 95 children. The varnish was reapplied every 3 months and the caries incr...

Plant-derived products can play an important role in pest management programs. Essential oils from Lavandula angustifolia (lavender) and Thymus vulgaris (thyme) and their main constituents, linalool and thymol, respectively, were evaluated for insecticidal activity and synergistic action in combination with insecticides against green peach aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae). ...

INTRODUCTION Jaundice is a disease named for the yellow color of the skin. This color is the result of elevated levels of bilirubin in the blood serum. In Roma from Krusevac region in the last few years have seen the emergence of jaundice. MATERIAL AND METHODS In 80 of them (40 suffering and 40 from control group) were performed tests of numerous parameters in the laboratories of the Health C...

Thyme (Thymus vulgaris L.) is a commonly used flavoring agent and medicinal herb. Several chemotypes of thyme, based on essential oil compositions, have been established, including (1) linalool; (2) borneol; (3) geraniol; (4) sabinene hydrate; (5) thymol; (6) carvacrol, as well as a number of multiple-component chemotypes. In this work, two different T. vulgaris essential oils were obtained fro...

GABA-activated RDL receptors are the insect equivalent of mammalian GABAA receptors, and play a vital role in neurotransmission and insecticide action. Here we clone the pore lining M2 region of the Varroa mite RDL receptor and show that it has 4 atypical residues when compared to M2 regions of most other insects, including bees, which are the major host of Varroa mites. We create mutant Drosop...

This study investigated the chemical composition, and antimicrobial activity against food-borne pathogens of essential oil isolated from heartwood Calocedrus formosana Taiwan. The oil, by hydrodistillation in a Clevenger-type apparatus, was characterized using GC–FID GC–MS. major constituents were τ-muurolol (16.1%), α-cadinol (11.1%), α-terpineol (10.6%), thymol (8.5%), β-thujaplicin (4.5%). d...

A number of benzoic acid analogues showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays. Structure-activity analysis revealed that antifungal activities of benzoic and gallic acids were increased by addition of a methyl, methoxyl or chloro group at position 4 of the aromati...

Morphological, chemical and genetic differences of 12 tree basil (Ocimum gratissimum L.) accessions were studied to determine whether volatile oils and flavonoids can be used as taxonomical markers and to examine the relationship between RAPDs to these chemical markers. Eugenol, thymol, and geraniol were the major volatile oil constituents found in Ocimum gratissimum. Xantomicrol and cirsimarit...