نتایج جستجو برای: thrombocytopenia

تعداد نتایج: 24759  

Journal: :Oncology 2015
David J Kuter

Thrombocytopenia is a common problem in cancer patients. Aside from bleeding risk, thrombocytopenia limits chemotherapy dose and frequency. In evaluating thrombocytopenic cancer patients, it is important to assess for other causes of thrombocytopenia, including immune thrombocytopenia, coagulopathy, infection, drug reaction, post-transfusion purpura, and thrombotic microangiopathy. The incidenc...

2015
Andreja Sinkovič Maja Majal

BACKGROUND In acute coronary syndromes (ACS), treated by combined antithrombotic therapy and percutaneous coronary interventions (PCI), thrombocytopenia may occur. Our aim was to evaluate predictors and the impact of thrombocytopenia on mortality in high-risk ACS patients. METHODS We retrospectively evaluated high-risk ACS patients. Thrombocytopenia was defined as platelet count <140.000/mL o...

Journal: :European heart journal 2014
Danny Dvir Philippe Généreux Israel M Barbash Susheel Kodali Itsik Ben-Dor Mathew Williams Rebecca Torguson Ajay J Kirtane Sa'ar Minha Salem Badr Lakshmana K Pendyala Joshua P Loh Petros G Okubagzi Jessica N Fields Ke Xu Fang Chen Rebecca T Hahn Lowell F Satler Craig Smith Augusto D Pichard Martin B Leon Ron Waksman

AIMS This study aimed to evaluate incidence and correlates for low platelet count after transcatheter aortic valve replacement (TAVR) and to determine a possible association between acquired thrombocytopenia and clinical outcomes. METHODS AND RESULTS Patients undergoing TAVR from two medical centres were included in the study. They were stratified according to nadir platelet count post proced...

Journal: :Pakistan postgraduate medical institute 2023

Objective: To determine the frequency of thrombocytopenia in confirmed cases malaria children&#x0D; Methods: This cross sectional study was conducted Pediatric Department Mayo Hospital Lahore from January to June 2018. A total 80 Children between two years- 12 years age, both genders with were included by non-probability consecutive sampling. blood sample taken within 48 hours admission and the...

Journal: :International journal of research publications 2022

Thrombocytopenia can increase the risk of bleeding. Determination type thrombocytopenia is important because it will affect patients treatment. The gold standard for distinguishing types bone marrow examination. This examination invasive and carries Platelet indices are simple less reliable in thrombocytopenia. aim this study to evaluate value platelet differentiating thrombocytopenia.This used...

Journal: :Blood 1980
P B Neame J G Kelton I R Walker I O Stewart H L Nossel J Hirsh

The mechanism of isolated thrombocytopenia in septicemia is unknown, but compensated disseminated intravascular coagulation (DIC) has been suggested as a possible cause. To investigate this possibility, platelet counts and sensitive assays for in vivo thrombin and plasmin generation, including fibrinogen gel chromatography and fibrinopeptide A (FPA) assays, were obtained on 31 septicemic patien...

Journal: :Blood 1981
J G Kelton D Meltzer J Moore A R Giles W E Wilson R Barr J Hirsh P B Neame P J Powers I Walker F Bianchi C J Carter

Thrombocytopenia is a common serious adverse effect of drug treatment. A variety of in vitro diagnostic techniques to confirm the diagnosis are available, but the majority lack sufficient sensitivity to detect all cases of drug-induced thrombocytopenia. We studied 19 patients with suspected drug-induced thrombocytopenia and demonstrated that platelet-associated IgG (PAIgG) was elevated in all a...

2015
Hong-Wei Fan Fu-Ping Guo Yi-Jia Li Ning Li Tai-Sheng Li

BACKGROUND The prevalence of thrombocytopenia among Chinese antiretroviral therapy (ART)-naïve HIV-infected adults has not been well-described. The aim of this study was to investigate the prevalence and associated risk factors of thrombocytopenia among Chinese ART-naïve HIV-infected adults. METHODS We performed a cross-sectional study of Chinese adult ART-naïve HIV-infected patients from Sep...

Journal: :Blood 1987
L Corash H Y Chen J Levin G Baker H Lu Y Mok

We have established a murine model and techniques with which to serially study thrombocytopoiesis after induction of experimental immune thrombocytopenia of variable severity and duration. Bone marrow megakaryocyte ploidy distribution was determined by using unfractionated bone marrow, a polyclonal megakaryocyte-specific probe, and two-color, fluorescence-activated flow cytometry. With these te...

2017
Cherisse Baldeo Karan Seegobin Lara Zuberi

Primary immune thrombocytopenia (ITP) - also called idiopathic thrombocytopenic purpura or immune thrombocytopenic purpura - is an acquired thrombocytopenia caused by autoantibodies against platelet antigens. It is one of the more common causes of thrombocytopenia in otherwise asymptomatic adults. Rocky Mountain spotted fever (RMSF) is a potentially lethal, but curable, tick-borne disease. We p...

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