Infection with the liver fluke Opisthorchis viverrini (Digenea) (Poirier, 1886) causes bile duct injury and periductal fibrosis by chronic overproduction of inflammatory-mediators and eventually results in cholangiocarcinoma development. While extensive research works have been done on O. viverrini infection-associated changes of bile ducts and periductal fibrosis, little attention was paid on ...

Exposure of perfused rat lungs to lipopolysaccharides (LPS) causes induction of cyclooxygenase-2 followed by thromboxane (TX)-mediated bronchoconstriction (BC). Recently, phosphodiesterase (PDE) inhibitors have received much interest because they not only are bronchodilators but also can suppress release of proinflammatory mediators. In the present study, we investigated the effect of three dif...

In breast cancer (BC), androgen receptor (AR) expression is related to estrogen receptor (ER) and/or progesterone receptor (PgR) expression. AR expression is an indicator of good prognosis in breast cancer regardless of hormone receptor (HR) status. In this study, we evaluated the effect of AR-related gene expression on clinical characterization of metastatic BC. We performed RNA-Seq to evaluat...

Abstract Background The role of viruses as a cause breast cancer (BC) has been significantly investigated in recent years. Human papillomavirus (HPV) detected invasive carcinomas, while most studies have only focused on the detection viral DNA, we aimed to examine prevalence and genotypes HPV among Iranian BC patients. We also examined presence herpes simplex-1 (HSV-1), simplex-2 (HSV-2), varic...

Bacterial cellulose (BC) grown from a culture medium in the presence of water-soluble poly(vinyl alcohol) (PVA) produced an assemblage that was used as precursor for the synthesis of biocompatible nanocomposites. Physical crosslinking via cyclic freezing and thawing of the formed hydrogel facilitated retention of PVA matrix upon composite separation and purification. The composites displayed a ...

CCDC170 and ESR1, located at 6q25.1, were associated with breast cancer (BC) risk by genome-wide association studies. Our goal was to validate the association between CCDC170-ESR1 polymorphisms and BC risk in the population of northwestern China. A case-control study of 551 patients with BC and 577 control individuals was conducted from January 2011 to November 2014. We analyzed five BC-associa...

The Wnt/beta-catenin (CTNNB1) and Ras-Raf-MEK-ERK signaling pathway play an important role in bladder cancer (BC) progression. Tumor-suppressive microRNAs (miRNAs) targeting these cancer pathways may provide a new therapeutic approach for BC. We initially identified miRNA-1826 potentially targeting CTNNB1, VEGFC and MEK1 using several target scan algorithms. Also 3' untranslated region lucifera...

Breast cancer (BC) is a disease that has improved prospects for survival if detected and treated early. Delayed help-seeking behavior, with poor survival as a consequence, is an important public health issue in the Middle East. More than 75% of breast cancer patients in the United Arab Emirates (UAE) seek medical advice after experiencing a sign or symptom of the disease and many seek such advi...

Meyer, S. L. F, D. P. Roberts, D. J. Chitwood, L. K. Carta, R. D. Lumsden, and W. Mao. 2001. Application of Burkholderia cepacia and Trichoderma virens , alone and in combinations, against Meloidogyne incognita on bell pepper. Nematropica 31:75-86. Bell pepper ( Capsicum annuum L.) seeds and seedlings were treated with three potentially beneficial microbes, applied alone and in combinations, to...

The study goal was to examine the association of three polymorphisms in the XRCC1 gene (Arg194Trp, Arg280His, and Arg399Gln) involved in repairing DNA damage produced by ionizing radiation, a known breast cancer (BC) risk factor, with BC incidence and the possibility of developing an adverse radiotherapy response. Genomic DNA from 254 BC cases, 70 of whom were adverse radiotherapy responders [r...