نتایج جستجو برای: thiotepa
تعداد نتایج: 617 فیلتر نتایج به سال:
extensive ischemic compromise, no resection should be done. Factors that seem to alter early survival are early diagnosis and anticoagulation, associated diseases and patient age. The relapse rate is high; thus, when a hereditary hypercoagulable state is detected, prolonged systemic anticoagulation should be maintained, while in other pro-thrombotic conditions 6 months of treatment provide adeq...
The title compound, C11H15N3OS, is a thio-semicarbazone derivative of the raspberry ketone rheosmin [systematic name: 4-(4-hy-droxy-phen-yl)butane-2-one]. The mol-ecule deviates from planarity, with the bridging C-C-C=N torsion angle equal to -101.3 (2)°. The maximum deviation from the mean plane of the non-H atoms of the thio-semicarbazone fragment [C=N-N-C(= S)-N] is 0.085 (5) Å for the Schif...
A new thyristor is proposed and realized in the foundry’s 0.18-μm CMOS process for electrostatic discharge (ESD) protection. Without extra mask layers or process steps, the new ultra-low-voltage-trigger thyristor (ULVT thyristor) has a trigger voltage as low as 6.7 V and an ESD robustness exceeding 50 mA/μm, which enables effective ESD protection. Compared with the traditional medium-voltage-tr...
A mutant P53 protein plays such a crucial role in ovarian cancer, and natural compounds have been known to be effective treating cancer. The current study was conducted discover new modulators plants used for medicinal purposes. p53 3D structure built using homology modeling, while its active binding domain predicted Findsitecom2.0. Docking studies were with ligands derived from bioactive compo...
A thiophosphoramide-based co-catalyst was found to significantly accelerate copper(II) trifluoromethanesulfonate-catalyzed arylation of potassium carboxylates with diaryliodonium salts. This effect could be attributed to counterion activation of diaryliodonium salts or organocopper intermediates by thiophosphoramides. Inclusion of thiophosphoramides permits achieving significantly milder reacti...
In recent years, a considerable amount of work has been done in order to elucidate the role of free radical intermediates in carcinogenesis 3. Particular ly, with the EPR technique a series of interesting but controversial results have been obtained 3. As a con sequence, to date, no conclusions can be made con cerning the role of free radicals and other paramagnetig species during the induct...
The effects of a pressurized suit on human performance were investigated. The suit is known as an Extra-Vehicular Mobility Unit (EMU) and is worn by astronauts while working outside their spacecraft in a low earth orbit. Isolated isokinetic joint torques of three female and three male subjects (all experienced users of the suit in 1G gravity) were measured while working at 100% and 80% of their...
EMT-6 murine mammary tumor sublines highly resistant to cyclophosphamide, cis-diamminedichloro-platinum(II), or N,N',N"-triethylenethiophosphoramide were generated in vivo by sequential treatment of tumor-bearing mice with the respective drugs. Previous studies demonstrated the drug-resistant phenotypes of the sublines were not expressed in vitro when the cells were grown as monolayer cultures....
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