Abstract The synthesis and characterization of three new inherently chiral N , N′ ‐dipropyl‐3,3′‐diheteroaryl‐2,2′‐biindole monomers, nicknamed Ind 2 T 4 6 Ph which differ in the number thiophenes as terminals, are reported. In addition to a full monomer characterization, stable electroactive oligomeric films were obtained by electro‐oxidation upon cycling potentials activate thiophene terminal...

That 3-[(t-butyldimethylsilyl)oxymethyl]furan 1_ can be lithiated at C-2 (n-BuLi/ether/r.t./6hj and the resulting anion quenched with electrophiles is well known. Treatment of the above anion with 1-bromo-3-chloropropane result ed in a poor yield of 2_; however, changing the reaction conditions (n-BuLi/THF 0°C/6h) and then adding HMPA with the electrophile resulted in the isolation o 1 (h0% by ...

Malaria is one of the world's most severe endemic diseases and due to the emergence of resistance to the currently available medicines, the need for new targets and relevant antimalarial drugs remains acute. The crude extract, four solvent fractions and two isolated compounds from the roots of Echinops hoehnelii were tested for their antimalarial activity using the standard four-day suppressive...

Thiophene-1,1-dioxide (TDO) oligomers have fascinating electronic properties. We previously used thermopower measurements to show that a change in charge carrier from hole to electron occurs with increasing length of TDO oligomers when single-molecule junctions are formed between gold electrodes. In this article, we show for the first time that the dominant conducting orbitals for thiophene/TDO...

Over the past 20 years, substantial progress has been made in the understanding of the activation of C-H and other strong bonds by reactive metal complexes in low oxidation states. This paper will present an overview of the use of pentamethylcyclopentadienyl and trispyrazolylborate rhodium complexes for the activation of arene and alkane C-H bonds. Insights into bond strengths, kinetic and ther...

The 1,1 carboboration reaction of a variety of metal-substituted alkynes with simple trialkylboranes R3B yields the respective alkenylboranes (Wrackmeyer reaction). The use of the strongly electrophilic R-B(C6F5)2 reagents allows for much milder reaction conditions and gives good yields of the respective bulky alkenylboranes from conventional terminal alkynes by means of 1,2-hydride migration. ...

Photolysis of S,C-sulfonium ylides derived from thioanisol, thiophene, benzothiophene, or dibenzothiophene provides products deriving from dicarbomethoxycarbene. In methanol, no rearrangement of the carbene to the ketene derivative is observed. Formation of dibenzothiophene and benzothiophene is quantitative. For the thiophene-based ylide, insertion of the carbene into the alpha-CH bond of thio...

Synthesis of 2,5-bisarylthiophenes was accomplished by sequential Suzuki cross coupling reaction of 2-bromo-5-chloro thiophenes. Density functional theory (DFT) studies were carried out at the B3LYP/6-31G(d, p) level of theory to compare the geometric parameters of 2,5-bisarylthiophenes with those from X-ray diffraction results. The synthesized compounds are screened for in vitro bacteria scave...

Six new thiophene oligomers, here designated as tripodal-like oligothienyl-imidazoles, were synthesized and have been investigated in ethanol solution at room and low temperature. The oligomers bear a common core where two or more thiophenes are linked to one or more imidazole units that further links through its alpha-position to a different number of incremental thiophene units. The study inv...