The introduction of intravenous cerebral thrombolysis (ICT) with recombinant tissue plasminogen activator (rt-PA) has constituted a milestone in the management of acute ischemic stroke, since both a randomized, controlled clinical trial and posterior studies conducted in the routine clinical practice setting have shown it to improve patient functional prognosis. ICT is moreover cost-effective a...

Pneumopericardium is an uncommon but potentially serious condition. It appears in association with invasive diagnostic and therapeutic procedures, although cases have also been reported in association with bronchospasm, esophageal disorders, and other problems. We describe a case of spontaneous pneumopericardium with chest pain in a patient with community-acquired pneumonia.

OBJECT scientific literature about crack abuse published in Brazilian journals indexed in SCIELO. OBJECTIVE systematic review of literature treating findings as a framework for agenda-setting orienting policy decision makers. METHODOLOGY SCIELO online journals research since 02/06/2013 on tag crack as "key word searched" and in indexes as "research amplitude". An amount of 199 references we...

Studies have shown that therapeutic hypothermia (TH) improves outcomes in patients who have experienced a cardiac arrest (; ). This article discusses TH and the process used by one emergency department to develop and implement an evidence-based protocol on TH for the postresuscitation patient.

This paper reports the findings of a small study undertaken in Scotland and England. The Maudsley Addiction Profile (MAP) and Lucid Adult Dyslexia Screening (LADS) were used to interview a small sample of 50 drug treatment service users. Half of the sample were residing in a therapeutic community (TC), whilst the other half were attending a community drug project and, almost exclusively, were r...

Psychosocial and pharmacological treatments for cocaine abuse are associated with high rates of attrition (e.g., Gawin et al. 1989; Higgins et al. 1993; Kang et al. 1991; Weddington et al. 1991). This is particularly unfortunate because poor drug abuse treatment retention is associated with poor outcomes. For example, several studies report that longer treatment duration predicts improved outco...

UNLABELLED The literature suggests that peer support is protective of relapse for adults treated for substance-use disorder. However, to our knowledge there is no standard measure of peer support. Therefore, the purpose of this research was to use Rasch analysis to assess a 13-item peer support scale used in a group of adults treated for primary psychoactive substance-abuse disorder. The partic...

Uncertainties associated with the effects from chronic low-level exposures to radiation prompted us to construct a Low Dose Rate Irradiation Facility (LoDIF). The facility was designed specifically to test the appropriateness of the 10 mGy d(-1) guideline often espoused as acceptable for protection of aquatic biota from ionizing radiation. Scientists at the 0.4 ha facility use 40 outdoor mesoco...

Research demonstrates that drug treatment staff members' knowledge and attitudes about methadone are positively correlated with treatment success among opiate-dependent clients. However the bulk of this research is on outpatient treatment in methadone clinics. This study examined a residential treatment program that allowed clients on methadone, a rare treatment opportunity that is growing nati...

saffron, the dried red-orange stigmas of crocus sativus l, has been known as a flavoring agent, food coloring and traditional herbal medicine. pharmacological effects of saffron are mainly attributed to crocin, crocetin, picrocrocin and safranal. these components especially crocin, have significant effects including antidepressant and anticonvulsant, analgesic, anti-cancer and other therapeutic...