Introduction Familial Mediterranean fever (FMF) is an autoinflammatory disease which is characterized by recurrent episodes of typical attacks with fever and abdominal pain. The pathophysiology shows an ineffective pyrin which leads to brakeless inflammation. It is not exactly known which factors lead to initiation of the attacks. Furthermore there seems to be sustained inflammation between the...

Soft l i thography is a low-cost, non-photolithographic strategy for carrying out micloand nano-fabrication. This unconventional approach consists oftechniques based on self-assembly and replica moiding oforganic molecules and polyneric marerialsFour such techniques, microcontact printing (ICP). replica molding. micromolding in capil laries (MIMIC), and microtransfer molding (ITM ). have been d...

The notion of cointegration has lead to a renewed interest in the identification and estimation of structural relations among economic time series, a field to which Henri Theil has made many pioneering contributions. This paper reviews the different approaches that have been put forward in the literature for identifying cointegrating relationships and imposing (possibly over-identifying) restri...

The article presents evaluation of digital inequality the Russian regions – subjects Russia. Digital has been assessed according to access Internet and technology which corresponds first level divide concept. Also, regions’ in effectiveness use technologie evaluated by gross value added under section “Information communication activities”. During stage study author analyzed 37 indicators charac...

This paper presents some aspects related to the issues of aggregating economic indicators. Departing from the research of Gh. Paun (1983) we will prove a theorem which states that under certain, natural assumptions, it is impossible to obtain an optimum aggregation. Unlike the original work of Paun, in this paper we are giving a rather simple proof of this theorem.