نتایج جستجو برای: theaflavin

تعداد نتایج: 200  

2017
Sabrina M Noritake Jenny Liu Sierra Kanetake Carol E Levin Christina Tam Luisa W Cheng Kirkwood M Land Mendel Friedman

BACKGROUND Plants produce secondary metabolites that often possess widespread bioactivity, and are then known as phytochemicals. We previously determined that several phytochemical-rich food-derived preparations were active against pathogenic foodborne bacteria. Trichomonads produce disease (trichomoniasis) in humans and in certain animals. Trichomonads are increasingly becoming resistant to co...

Journal: :Toxicology and applied pharmacology 2007
Meng-Shih Weng Chi-Tang Ho Yuan-Soon Ho Jen-Kun Lin

Fatty acid synthase (FAS) is a major lipogenic enzyme catalyzing the synthesis of long-chain saturated fatty acids. Most breast cancers require lipogenesis for growth. Here, we demonstrated the effects of theanaphthoquinone (TNQ), a member of the thearubigins generated by the oxidation of theaflavin (TF-1), on the expression of FAS in human breast cancer cells. TNQ was found to suppress the EGF...

2013
Amit Kumar Srivastava Priyanka Bhatnagar Madhulika Singh Sanjay Mishra Pradeep Kumar Yogeshwer Shukla Kailash Chand Gupta

In spite of proficient results of several phytochemicals in preclinical settings, the conversion rate from bench to bedside is not very encouraging. Many reasons are attributed to this limited success, including inefficient systemic delivery and bioavailability under in vivo conditions. To achieve improved efficacy, polyphenolic constituents of black (theaflavin [TF]) and green (epigallocatechi...

2015
Madhulika Singh Priyanka Bhatnagar Sanjay Mishra Pradeep Kumar Yogeshwer Shukla Kailash Chand Gupta

The clinical success of the applicability of tea polyphenols awaits efficient systemic delivery and bioavailability. Herein, following the concept of nanochemoprevention, which uses nanotechnology for enhancing the efficacy of chemotherapeutic drugs, we employed tea polyphenols, namely theaflavin (TF) and epigallocatechin-3-gallate (EGCG) encapsulated in a biodegradable nanoparticulate formulat...

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