There is an increasing trend to apply gas chromatography combined with mass spectrometry (GC-MS) or liquid chromatography tandem mass spectrometry (LC-MS/MS) assay methods to large-scale epidemiologic studies for the measurement of serum sex steroids. These methods are generally considered the gold standard for sex steroid measurements because of their accuracy, sensitivity, turnaround time, an...

Increased activity of hepatic microsomal enzymes can be evaluatedby measuring D-giucaric acidexcretionin urine and y-glutamyltransferase (EC 2.3.2.2) activity in serum. AsIde from diverse foreign compounds, endogenous steroid hormones have been shown to be normal substrates of the microsomal enzyme system. Because there is an increase In steroid production In pregnancy, we sought to determine w...

     This Study was performed to evaluate the effect of atenolol on the serum concentration of TT4 and TT3 in subclinical hyperthyroid patients. Due to the i n s u fficient information about the effect of atenolol on serum level of these hormones, the aim of this research was to shade some light on the subject. Fifteen subclinical hyperthyroid patients entered this study. Each patient received ...

Well-established associations between reproductive characteristics and epithelial ovarian cancer (EOC) support an involvement of sex steroid hormones in the etiology of EOC. Limited previous studies have evaluated circulating androgens and the risk of EOC, and estrogens and progesterone have been investigated in only one of the previous studies. Furthermore, there is little data on potential he...

The association between steroid hormones and cancer has been a primary research focus for many years. Reproductive are of particular interest given the fact that several highly prevalent c...

Introduction: During the menstrual cycle, women are exposed to continual variations in serum concentrations of various female sex steroid hormones. The fluctuations main hormones, estrogen, progesterone, follicle stimulating hormone and luteinizing hormone, essential for regulating ovulatory cycle patterns. In this sense, it is speculated that strength training can stimulate signaling pathways ...

One hundred and forty seven clinically proven hyperthyroid subjects were studied using radioimmunoassay techniques for the estimation of serum thyroid hormones and pituitaryTSH concentrations. In females toxic goitre was more frequently seen in the age group 21 to 30 years and in males 31 to 40 years. The mean levels for serum T4, T3, FT4 and FT1 were significantly elevated while the mean level...

BACKGROUND Beta-thalassemia is the most common hematology disease in human and leptin is one of the hormone that produce by adiposities cells. The purpose of this study was to investigate the relationship between serum leptin level and thyroid hormones in children with major beta-thalassemia. MATERIALS AND METHODS This descriptive-cross sectional study was performed on 90 children aged 6-16 y...