Early auditory deprivation and a delay in language acquisition may result in disturbances to the normal development of executive function behaviors in congenitally deaf children with cochlear implants. The purpose of this study was to examine the relationship between executive function and spoken language processing using two new executive function measures, the Self-Ordered Pointing (SOP) and ...

BACKGROUND Favorable results of treatment with bosentan in patients with Eisenmenger syndrome are available. However, data in Down patients are lacking. In this study, we evaluate the therapeutic role of bosentan treatment in Down patients with Eisenmenger syndrome. METHODS In this open-label study, 24 Down patients (>18 years) with Eisenmenger syndrome (17 males) were treated with bosentan. ...

Background: The minimum clinically important difference (MCID) for the St George’s Respiratory Questionnaire (SGRQ) is debated in chronic obstructive pulmonary disease (COPD) quality-of-life (QoL) assessments. This study aimed to determine whether there a predictors of significant improvement between traditional (value 4) and newly proposed MCID SGRQ 7) after climatic rehabilitation treatment. ...

For the bottleneck problem of the conversion efficiency in silicon-based solar cell, the Metallization Wrap– through (MWT) technology is one of the effective methods based on the analysis of factors affecting the solar cell conversion efficiency. The MWT technology is based on laser perforation and that the bus grid lines in the front surface of the solar cell are moved to the back surface. The...

Harpagophytum procumbens, also known as Devil's Claw, has historically been used to treat a wide range of conditions, including pain and arthritis. The study was designed to investigate whether H. procumbens extracts exhibit analgesic effects in plantar incision and spared nerve injury (SNI) rats. The whole procedure was performed on male SD rats. To evaluate pain-related behavior, we performed...

The current study was designed to investigate whether edible brown seaweed Ecklonia cava extracts exhibits analgesic effects in plantar incision and spared nerve injury (SNI) rats. To evaluate pain-related behavior, we performed the mechanical withdrawal threshold (MWT) and thermal hypersensitivity tests measured by von Frey filaments and a hot/cold plate analgesia meter. Pain-related behavior ...

The wheel tracking test (WTT) has been extensively used for laboratory characterization of permanent deformation hot mix asphalt (HMA). However, the fully-confined setup device is unable to capture tertiary zone where shear takes place. This makes resistance characteristics HMA difficult analyze. Hence, a modified tracker (MWT), with unconfined lateral sides along direction was utilized in this...

Experimental and computational approaches to estimate solubility and permeability in discovery and development settings are described. In the discovery setting ‘the rule of 5’ predicts that poor absorption or permeation is more likely when there are more than 5 H-bond donors, 10 H-bond acceptors, the molecular weight (MWT) is greater than 500 and the calculated Log P (CLogP) is greater than 5 (...

PURPOSE To compare black-blood multicontrast carotid imaging at 3T and 1.5T and assess compatibility between morphological measurements of carotid arteries at 1.5T and 3T. MATERIALS AND METHODS Five healthy subjects and two atherosclerosis patients were scanned in 1.5T and 3T scanners with a similar protocol providing transverse T1-, T2-, and proton density (PD)-weighted black-blood images us...