Abstract Introduction Brucella epididymo-orchitis is a complication that occurs in 5.7% of patients with brucellosis and can rarely mimic testicular tumor. We here report case 25-year-old man presented as mass responded to conservative treatment using antibiotic therapy. Case A patient left pain, abdominal easy fatiguability, feeling unwell. Physical examinations were normal. tumor was suggeste...

The de novo synthesis of glycerolipids in mammalian cells begins with the acylation of glycerol-3-phosphate, catalyzed by glycerol-3-phosphate acyltransferase (GPAT). GPAT2 is a mitochondrial isoform primarily expressed in testis under physiological conditions. Because it is aberrantly expressed in multiple myeloma, it has been proposed as a novel cancer testis gene. Using a bioinformatics appr...

three lymph nodes was also found in 14 examined mesenteric lymph nodes. The patient received postoperative chemotherapy that consisted of 12 cycles of mFOLFOX6. He was doing well during follow-ups and remained no recurrence at 20 months after surgery. Reports on metastatic cancer of the testis, as analog Krukenberg tumor in male, are rare. Cryptorchid testicular metastasis, as a special type of...

Tumor vaccines represent one type of molecularly targeted therapy being investigated for the treatment of prostate cancer. Although many prostate-specific proteins are being tested as target antigens for prostate cancer vaccines, most are not natural targets of an immune response in patients with cancer. Using sera from cancer patients, several research groups have identified a large family of ...

parenchyma immediately adjacent to the cysts showed decreased echogenicity compared with the parenchyma elsewhere with multiple microcysts communicating with solid lesions of mixed echogenicity, highly suspicious for malignancy. Computed tomography (CT) of the chest, abdomen, and pelvis showed no abnormal findings. In agreement with the patient, we decided to perform a bilateral testicular ingu...

The success of immunotherapy in Hodgkin lymphoma is hampered partly by limited expression of tumor-specific antigens in the malignant cells. One strategy to increase tumor immunogenicity may be to enhance the expression of Hodgkin lymphoma-specific antigens such as MAGE-A4 using epigenetic-modifying drugs in combination with cancer testis antigen-specific immunotherapy.

By describing 3 clinical cases of unusual testicular non germinal tumors, including an adenoma of the rete testis, an undifferenciated sex cord tumor and a mesothelioma of the tunica vaginalis, we make a literature review of the unusual testicular tumors and testicular apendix, including their incidence and management. Also and as one of our conclusions, we expose the importance of the intraope...

PURPOSE To evaluate if 18 fluorodeoxyglucose positron emission tomography (18FDG-PET) scan could identify post-chemotherapy retroperitoneal lymph node (RPLN) involvement in advanced germ cell tumors of the testis. MATERIALS AND METHODS Between January 2005 and January 2009, 16 patients with advanced germ cell tumors of the testis underwent RPLN dissection (RPLND) following chemotherapy. Befor...

When cells of the Walker 256 rat tumor were incu bated in vitro with neuraminidase, free sialic acid accu mulated in the medium without detectable loss of tumor cell viability, as indicated by the unchanged survival of rats given i.p. injections of 50, 100, or 250 cells. For de termination of the effect of neuraminidase treatment of the tumor cells on their adherence to living mesothelium, 1 te...