The initial genomic response to serum growth factors is the transcriptional activation of a set of immediate-early genes. Serum-induced transcriptional activation of several of these genes involves the formation of a ternary complex that includes the serum response factor (SRF), a 62 kDa ternary complex factor (TCF) and a serum response element (SRE). TCF alone does not bind the SRE of the prot...

Strong demand for power reduction in state-of-the-art semiconductor devices calls for novel devices and architectures. Since ternary logic architecture can perform the same function as binary logic architecture with a much lower device density and higher information density, a switch device suitable for the ternary logic has been pursued for several decades. However, a single device that satisf...

We discuss the implications of the recent upward revision of the LMC microlensing rate by the MACHO Collaboration. We conclude: (i) A good case for the existence of baryonic dark matter in the halo has been made; (ii) The case for the existence of cold dark matter is unaffected and still compelling; and (iii) The Galactic halo is still an excellent place to search for cold dark matter particles...

The dilator function of the vascular endothelium is critical for optimal tissue perfusion, and this is brought into stark reality in a number of diseases, such as hypertension, diabetes, and preeclampsia, in which endothelium-dependent vasodilator function is impaired. Prostacyclin and nitric oxide (NO) were the earliest identified endothelium-dependent vasodilators, but it was soon found that ...

An anticipatory system for guiding plot development in interactive narratives is described. The executable model is a finite automaton that provides the implemented system with a lookahead. The identification of undesirable future states in the model is used to guide the player, in a transparent manner. In this way, too radical twists of the plot that lead to behaviors of the autonomous fellow ...

YAKOV RAPOPORT, The doctors'plot, transl. Natina Perova and Raissa Bobrova, London, Fourth Estate, 1991, pp. xii, 280, illus., £17.95 (1-872180-13-2). On 13 January 1953, the astounded citizens of the USSR heard a massive "criminal conspiracy" denounced. Prominent Soviet physicians had conspired to kill the leaders of the country by medical means. A round of arrests followed involving high-rank...