This report presents estimates of the prevalence of heart and other cikculatory conditions of children and ycpuths age 6 through 17 years in the' ioninstitutionalized population of the U.S. Estimatei are based on diagnostic impression data from the direct, standardized examination findings of the Health Examination Surveys among national probability samples representative of the 23.8 children a...

A number of recessive autosomal genes cause male infertility. Male mice homozygous for the blind-sterile (bs/bs) and quaking-sterile (qk/qk) gene mutations are sterile, because they either do not produce any spermatozoa or produce only a few abnormal spermatozoa. Mice lacking the cyclic AMP responsive-element modulator gene are sterile due to failure of spermiogenesis. All these mice, however, ...

BACKGROUND Some studies, but not all, support the hypothesis that trisomy frequency is related to the size of the oocyte pool, with the risk increased for women with fewer oocytes (older ovarian age). We tested this hypothesis by comparing hormonal indicators of ovarian age among women who had trisomic pregnancy losses with indicators among women with non-trisomic losses or chromosomally normal...

Opioid peptides have been reported to have important functions in human reproduction. Indeed, very high concentrations of enkephalins and their degrading enzymes have been reported in human semen. In the present paper, we compare the activity of two enkephalin-degrading enzymes, aminopeptidase N and neutral endopeptidase 24.11, in different fractions of semen from normozoospermic, fertile men a...

Background: Male infertility associated with sperm DNA alteration has raised a new issue in assisted reproduction techniques (ARTs).Methods: It was retrospective analytical study on 250 cases of routine IVF/ICSI performed at Swagat ART Centre from January 2017 to 2020. We divided the patient according fragmentation index (DFI) as normal DFI≤15%, n=95, moderate DFI≤30%, n=89, and high DFI group ...

Single structural defects involving the totality of ejaculated sperm are among rare cases of untreatable human male infertility. This form of infertility is of genetic origin and is generally transmitted as an autosomal recessive traits. Acrosome agenesis or globozoospermia results from perturbed expression of nuclear proteins or from an altered Golgi-nuclear recognition during spermiogenesis. ...

BACKGROUND Fertilization, cell division and embryo development depend on genomic contributions from male and female gametes. We hypothesize that teratozoospermic sperm influences early embryo development and embryo compaction. METHODS We conducted a retrospective analysis of embryos derived from intracytoplasmic sperm injection (ICSI) cycles. Two hundred thirty-five consecutive ICSI cycles we...