Topological properties of DNA influence its mechanical and biochemical interactions. Genomic DNA is maintained in a state of topological homeostasis by topoisomerases and is subjected to mechanical stress arising from replication and segregation. Despite their fundamental roles, the effects of topology and force have been difficult to ascertain. Developments in single-molecule manipulation tech...

BACKGROUND Programs for improving health status of patients with illness related to pain, such as headache, are often still in their infancy. Mindfulness-based stress reduction (MBSR) is a new psychotherapy that appears to be effective in treating chronic pain and stress. This study evaluated efficacy of MBSR in treatment of perceived stress and mental health of client who has tension headache....

The role of 5-fold twin boundary on the structural and mechanical properties of fcc Fe nanowire under tension is explored by classical molecular dynamics. Twin-stabilized fcc nanowire with various diameters (6-24 nm) are examined by tension tests at several temperatures ranging from 0.01 to 1100 K. Significant increase in the Young's modulus of the smaller nanowires is revealed to originate fro...

A three-dimensional stress-concentration analysis was conducted on straight-shank and countersunk (rivet) holes in a large plate subjected to various loading conditions. Three-dimensional nite-element analyses were performed with 20-node isoparametric elements. The plate material was assumed to be linear elastic and isotropic, with a Poisson's ratio of 0.3. Stress concentrations along the bore ...

BACKGROUND Patients with borderline personality disorder frequently show non-suicidal self-injury (NSSI). In these patients, NSSI often serves to reduce high levels of stress. AIMS Investigation of neurobiological mechanisms of NSSI in borderline personality disorder. METHOD In total, 21 women with borderline personality disorder and 17 healthy controls underwent a stress induction, followe...

To design more effective tissue-engineered heart valve replacements, the replacement tissue may need to mimic the biaxial stress-strain behavior of native heart valve tissue. This study characterized the planar biaxial properties of tissue-engineered valve leaflets and native aortic valve leaflets. Fibrin-based valve equivalent (VE) and porcine aortic valve (PAV) leaflets were subjected to incr...

Stress fractures have been reported in the upper limb of sportspeople involved in upper limb dominated events. Olecranon stress fractures have been cited in baseball pitchers, javelin throwers, and gymnasts. The unusual case of a stress fracture of the olecranon in a young weight lifter is reported here. The minimally displaced stress fracture was treated with tension band and two Kirschner wir...

Following a step increase in sarcomere length, isometric cardiac muscle tension increases instantaneously by the Frank-Starling mechanism. In isolated papillary muscle and myocytes, there is an additional significant rise in developed tension over the following 15 min due to an unknown mechanism. This slow change in tension could not be explained by mechanical heterogeneity of the muscle prepar...

The aim of this study was to clarify the association between sleeping time and job stress in male Japanese workers. Male workers at one manufacturing plant were surveyed about job stress and sleeping time using a selfcompleted questionnaire. A total of 274 white-collar daytime workers were analyzed. Job stress factors and stress response were assessed using the Job Stress Questionnaire. Sleepin...

Normal 0 false false false EN-US X-NONE AR-SA The ratio of compression yield strength to the initial tensile yield strength is called Bauschinger effect factor, BEF. A nonlinear strain hardening mathematical model is proposed for 7075 aluminium alloy (A7075). Uniaxial tension-compression experimental data are used to figure out a suitable model to study the BEF. Hence, uniaxial tension-co...