Anisotropic colloidal building blocks are quite attractive as they enable the self-assembly towards new materials with designated hierarchical structures. Although many advances have been achieved in colloidal synthetic methodology, synthesis of colloidal rings with low polydispersity and on a large scale remains a challenge. To address this issue we introduce a new site-selective growth strate...

In analogy to proteins, the function of RNA depends on its structure and dynamics, which are encoded in the linear sequence. While there are numerous methods for computational prediction of protein 3D structure from sequence, there have been very few such methods for RNA. This review discusses template-based and template-free approaches for macromolecular structure prediction, with special emph...

Ubiquitous monitoring has become a useful tool for the prevention and early diagnosis of some disorders. This kind of monitoring has been promoted last years thanks to the irruption of the smartphones, which make easier the collection and delivery of the patient’s data. However, there are some problems with the quality of the acquired data. This paper presents a novel methodology in which the s...

We report the one-pot amplification and isolation of a nanomolar receptor in a multibuilding block aqueous dynamic combinatorial library using a polymer-bound template. By appropriate choice of a poly(N,N-dimethylacrylamide)-based support, nonselective ion-exchange type behaviour between the oppositely charged cationic guest and polyanionic hosts was overcome, such that the selective molecular ...

Depending on whether similar structures are found in the PDB library, the protein structure prediction can be categorized into template-based modeling and free modeling. Although threading is an efficient tool to detect the structural analogs, the advancements in methodology development have come to a steady state. Encouraging progress is observed in structure refinement which aims at drawing t...

MicroRNA (miRNA) was a promising class of cancer biomarkers. Here we developed a label-free method for sensitive measurement of let-7d miRNA based on multiple amplification techniques. The primer will bind to the duplex strand DNA that was formed by stem-loop template and target let-7d to initiate strand displacement amplification (SDA) in tandem. The released single strand DNA will be a primer...

BACKGROUND The information contained in histopathology reports on surgical resections of cancer is fundamental for both patient treatment and cancer registries. Electronic synoptic histopathology reporting is considered superior to traditional narrative reporting with respect to both completeness and feasibility of data use. An electronic template for colorectal cancer reporting was introduced ...

Purpose Many management scholars view templates as rigid rulebooks suffocating qualitative research. This viewpoint article recommends that, instead, should be viewed through the lens of organizational routines. Design/methodology/approach To facilitate this viewpoint, first clarifies confusions surrounding templates. It points out that how using templates, like following routines in an organiz...

KEMI-TORNIO UNIVERSITY OF APPLIED SCIENCES Degree programme: Business Information Technology Writer: Cristian-Stefan Marin Thesis title: Microsoft Windows Azure cloud application development and security concepts Pages (of which appendices): 82 (5) Date: Thesis instructor: Roger Niska This thesis focuses on the area of cloud computing, an important and relevant research area in computer science...