نتایج جستجو برای: temperature fixed at 15oc vaccine titers
تعداد نتایج: 4164500 فیلتر نتایج به سال:
Histophilosis, a mucosal and septicemic infection of cattle is caused by the Gram negative pathogen Histophilus somni (H. somni). As existing vaccines against H. somni infection have shown to be of limited efficacy, we used a reverse vaccinology approach to identify new vaccine candidates. Three groups (B, C, D) of cattle were immunized with subunit vaccines and a control group (group A) was va...
Outer membrane proteins (OMPs) of Pasteurella multocida play an important role in virulence and are for vaccine development due to immunogenicity. Here, we evaluated immunoprotection mice, immunized with native OmpH, recombinant OmpH HS alum precipitated P. P52 against challenge. Protection studies were performed mice groups I (OmpH); II (recombinant OmpH); III (HS vaccine). Group IV was contro...
In the present study, the potency and immunogenicity of the inactivated bivalent vaccine of Newcastle disease (ND) and avian influenza (AI) produced by Razi institute in Iran were compared with a similar imported vaccine administered by standard methods to specific-pathogen-free (SPF) chicken. A total of 150 twenty-one-day-old SPF chickens were used for evaluating Razi and imported inactivated ...
Children with sickle cell disease were immunized with either 2 doses of 7-valent pneumococcal conjugate vaccine followed by 1 dose of 23-valent pneumococcal polysaccharide vaccine or a single dose of 23-valent vaccine. Functional antibodies to 7 vaccine serotypes were measured by a flow cytometric opsonophagocytic assay (OPA) and compared with IgG anticapsular polysaccharide antibody concentrat...
Small adult dogs between 3 and 9 years of age, participated in a clinical research study to determine whether giving them just a half-dose of a bivalent canine distemper and parvovirus vaccine (DPV) generated a protective serum antibody titer response 1 and 6 months later in comparison to pre-vaccination titer levels. None of these dogs had received a vaccination for at least 3 years, and all w...
In this study we describe the immunogenicity results from a subset of older people (N = 5187) who participated in a Phase 3 randomized, observer-blinded trial of AS03-TIV versus TIV (Fluarix™) (ClinicalTrials.gov, NCT00753272). Participants received one dose of AS03-TIV or TIV in each study year and antibody titers against the vaccine strains were assessed using hemagglutination-inhibition (HI)...
TRIAL DESIGN In an earlier trial, Papua New Guinean (PNG) children at high risk of pneumococcal disease were randomized to receive 0 or 3 doses of 7-valent pneumococcal conjugate vaccine (PCV7), followed by a single dose of 23-valent pneumococcal polysaccharide vaccine (PPV23) at 9 months of age. We here studied in a non-randomized follow-up trial the persistence of pneumococcal immunity in the...
Our objective was to investigate the effect of various reimmunization schemes for hepatitis B in adults with low or undetectable anti-HBs titers. Over 2 years, 10 μg of Saccharomyces cerevisiae-recombinant hepatitis B virus (HBV) vaccine (synthesized in China) was used in at least one standardized scheme to immunize 2,310 healthy male and nonpregnant female adults. Of these, 240 subjects tested...
BACKGROUND Japanese encephalitis (JE) is a vaccine-preventable acute disease. We report the results of a phase 2/3 trial of JENVAC, a Vero cell-derived vaccine developed using an Indian strain of JE virus (JEV). METHODS JENVAC was administered in 2 doses 28 days apart, and immunogenicity was compared to that from a single dose of SA-14-14-2, the only approved JE vaccine and regimen at the tim...
Antibody responses in sixty clinically healthy pregnant sheep and goats were compared following the administration of enterotoxaemia vaccine. The thirty animals of each species were randomly divided into three groups. Antibody titers against C. perfringens type D epsilon toxin were detected in blood samples on day 15, 30, 45, 60 and 75 post vaccination. In unvaccinated control groups, S-I (shee...
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