Heroin addicts consume large quantities of refined sugars. This study investigated the effect of opiate use and antagonism on sweet taste in opiate-maintained drug users and detoxified former chronic opiate users, using a within-subject design. Seven opiate users received methadone and seven buprenorphine maintenance. Six detoxified subjects received naltrexone. Sucrose recognition thresholds a...

Research has demonstrated that individuals with eating disorders have an impaired sense of smell and taste, though the influence of eating attitudes, dietary restraint and gender in a non-clinical sample is unknown. In two studies (study 1: 32 females, 28 males; study 2: 29 females) participants completed questionnaires relating to Eating Attitudes (EAT) and dietary restraint (DEBQ) followed by...

Human and rat have an innate preference for fat which may lead to obesity. This preference may be driven by the taste component linoleic acid, the principle free fatty acid found in corn oil. It has been shown that rats are capable of detecting linoleic acid within a solution. It is speculated that rats also perceive an increase in intensity when linoleic acid is added to the solution. This exp...

Popular science has emphasized the risks of high sodium intake and many studies have confirmed that salt intake is closely related to hypertension. The present mini-review summarizes experiments about salt taste sensitivity and its relationship with blood pressure (BP) and other variables of clinical and familial relevance. Children and adolescents from control parents (N = 72) or with at least...

BACKGROUND Chlorpheniramine maleate (CM) is widely used as an antihistaminic drug but it is very bitter and as yet no mouth dissolving/disintegrating taste-masked preparation that might be useful for pediatric and geriatric patients is available in the market. OBJECTIVES The purpose of this research was to mask the bitter taste of CM by formulating microspheres of the taste-masked drug. MAT...

In frogs, the glossopharyngeal nerve (GL) innervates taste receptors on almost the entire tongue. The mandibular branch (MBF) and palatine branch (PN) of the facial nerve innervate taste receptors on a very small area at the base of the tongue and on the palate, respectively. In the present study, effects of amiloride, an epithelial sodium channel blocker, on the tonic responses of the GL, MBF ...

The preference of sweet taste in rats is a phenomenon that is influenced by many factors. Drugs, sex, and age are three important aspects to consider when determining the underlying mechanisms that influence increased intake in the presence of sweet taste. Research has shown that drugs acting on receptors and neurotransmitters of brain mechanisms relevant to hedonic and reinforcement effects ca...

Remove ‘dietary nutrient’ consumption and replace with ‘food habits’ (since an FFQ was used). Insert ‘(sweet)’ after sucrose. Replace ‘perception’ threshold with ‘detection’ threshold. Corrections are done (Page 2, paragraph 1, line 7, 9, 11,12,13, 16, 17) Introduction Reference all background statements. Corrections are done, we added bibliography: 11. Sherry VW: Taste alterations among patien...

To study Salt Taste Threshold (STT) and its relation to Blood pressure (BP) in normotensive adolescents, age and BMI matched 60 subjects of 18-20 years were segregated on basis of family history of hypertension, documented risk factor for development of hypertension. Student's unpaired t-test showed that STT and BP values were significantly higher in Hypertensive offspring group than Control. P...

Since,by applying the integrator recording method to the quantitative study of the taste receptors of rat's tongue,BEIDLER(1953)confirmed that cations appear to have the greater effectiveness than anions for stimulating the chemoreceptors,the similar experiments have been carried out on several other animals by a number of investigators(BEIDLER,FISHMAN and HARDIMAN, 1955;FISHMAN,1957;TATEDA,196...