نتایج جستجو برای: targeted delivery

تعداد نتایج: 344312  

Journal: :Research and analysis journal 2023

Brain is the most sophisticated and important organ of our body. Together with spinal cord it control all actions, functions voluntary or involuntary plays a vital role in managing various systems It has its own protective barriers that protects brain from pathogens toxins may cause harm. These are namely Blood-Brain barrier Blood-Cerebrospinal Fluid Barrier. The highly lipophilic nature these ...

A. Rashti H. Montazeri M. Mehrabi N. Mohamadpour Dounighi, R. Vakili-Ghartavol

Most infectious diseases are caused by pathogenic infiltrations from the mucosal tract. Nowadays, the use of vaccines has been widely investigated for the prevention of different infectious diseases, infertility, immune disorders, malignancies, and allergies. Broad-spectrum adjuvant substances have been studied for immune system stimulation with a greater efficiency against specific antigens. V...

Kavussi, Hamid Rreza, Miresmaeili, Seyed Mohsen, Nikoonahad Lotfabadi, Narges, Heydari khormizi, Nasrin ,

Introduction: In recent years, the treatment strategy for infectious and autoimmune diseases has significantly changed. Up to now, cancer treatment has been conducted on the basis of clinical and pathological methods. The most common cancer treatments is limited to chemotherapy, radiation therapy and surgery. However, cancer treatment is still not optimal. Common challenges for treatment of cer...

2016
Sudhakar Godeshala Rajeshwar Nitiyanandan Brian Thompson Sheba Goklany David R. Nielsen Kaushal Rege

Targeted delivery of anticancer therapeutics can potentially overcome the limitations associated with current chemotherapeutic regimens. Folate receptors are overexpressed in several cancers, including ovarian, triple-negative breast and bladder cancers, making them attractive for targeted delivery of nucleic acid therapeutics to these tumors. This work describes the synthesis, characterization...

2016
Sugapriya Dhanasekaran

Introduction: Targeted drug delivery systems are nanoscale drug carrier molecules designed for improving the communication of cellular and molecular components and biodistribution of tumour targeted drug (chemo) therapeutics. Nanomaterials are generally clusters of molecules, atoms and molecular fragments into extremely small size particles (1-100 nm) in nature. Nanomaterials engineered as self...

The aim of this study was to investigate the interaction modification of curcumin complex molecule (CUR) in beta- and gamma-cyclodextrin (β-CD and γ-CD) carriers with chitosan (CS) nanoparticles for targeted drug delivery and to compare their performance. The targeted drug delivery system includes the therapeutic agent of the CS nanoparticles targeting section of the same drug and the CD carrie...

Bioactive products from snail slime of “Helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. However, the poor pharmacokinetics characteristics of these natural compounds limit their use. Nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug del...

Journal: Nanomedicine Journal 2017

Objective(s): One applications of nanotechnology is in the area of medicine which is called nanomedicine. Primary instruments in nanomedicine can help us to detect diseases and used for drug delivery to inaccessible areas of human tissues. An important issue in simulating the motion of nanoparticles is modeling blood flow as a Newtonian or non-Newtonian fluid. Sometimes blood flow is simulated ...

Bioactive products from snail slime of “Helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. However, the poor pharmacokinetics characteristics of these natural compounds limit their use. Nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug del...

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