Dracocephalum kotschyi (Lamiaceae), as one of the remarkable aromatic plants, widely grows and also is cultivated in various temperate regions of Iran. There are diverse reports about the composition of the oil of this plant representing limonene derivatives as its major compounds. There is no report on cloning of monoor sesquiterpene synthases from this plant. In the present study, the aroma p...

BACKGROUND A number of medicinal plants have been used to treat various immunological diseases. Nitric oxide (NO) has an important regulatory role in the various types of inflammatory processes. OBJECTIVE To investigate the NO modulatory activity of the extracts of several medicinal plants native to Iran including Dracocephalum kotschyi, Linum persicum, Dionysia termeana, Salvia mirzayanii, F...

Four LMW-m and one novel chimeric (between LMW-i and LMW-m types) low-molecular-weight glutenin subunit (LMW-GS) genes from Aegilops neglecta (UUMM), Ae. kotschyi (UUSS), and Ae. juvenalis (DDMMUU) were isolated and characterized. Sequence structures showed that the 4 LMW-m-type genes, assigned to the M genome of Ae. neglecta, displayed a high homology with those from hexaploid common wheat. Th...

From ancient times to the present, plants have been used in many different areas. One of most striking these areas use is alternative medicine. Turkey a country rich both terms location and other favorable conditions. This wealth reveals importance In this context, it very important determine pharmacological properties plants. our study, total antioxidant status (TAS), oxidant (TOS), oxidative ...

Free radical scavenging and cell aggregation inhibitory activities of 36 secondary metabolites isolated from the methanolic extracts of Verbascum cilicicum Boiss., V. lasianthum Boiss. ex Bentham, V pterocalycinum var. mutense Hub.-Mor., and V. salviifolium Boiss. (Scrophulariaceae) were investigated. The isolated compounds, 6-O-vaniloyl ajugol (1), ilwensisaponin A (2), ilwensisaponin C (3), v...

BACKGROUND Since ancient times, various infectious diseases have been treated using herbal drugs. Today, efforts regarding the discovery of the effectual components of plants possessing antimicrobial properties are advanced. Herbal essential oils are widely used for treatment of various diseases, and they play an important role in health care considerations. METHODS The antibacterial activity...

BACKGROUND The Candida species are the most important factors of fungal infections in humans and animals. It is necessary to prepare antifungal or antimicrobial drugs because of increasing drug resistance. The natural treatment of diseases of bacterial origin using medicinal plants is important. In this study the effect of antimicrobial medicinal herbal essential oils and conventional antifunga...

The fruiting branches of Colutea cilicica Boiss. & Bal., along with leaves and fruits, have been used to heal inflammatory wounds at traditional medicine in various parts of Turkey. In order to evaluate the wound healing activity of the plant, aqueous extracts were prepared from the flowering parts and fruits of Colutea cilicica Boiss. & Bal. by using 40°C distilled water. Incision wound healin...

Resistance to chemotherapy and recurrence are major hurdles treating hormone receptor-negative breast cancer. The crude extract natural products obtained from medicinal plants believed be multitargeted possess less toxicity as compared synthetic compounds. aerial parts roots of Moricandia sinaica (Boiss.) Boiss were used prepare the extracts in solvents different polarities. Human cancer cell l...