Strains of Escherichia coli which lack the dam-encoded adenine methylase are mutators due to a reduction in the efficiency of postreplication mismatch repair. In this study, we show that Dam(-) strains are also defective in very-short-patch repair, the system which corrects T/G mismatches arising from the deamination of 5-methylcytosine. This defect is associated with decreased levels of Vsr, t...

Abstract: Noise filtering, data predicting, and unmonitored data interpolating are important to dam deformation data analysis. However, traditional methods generally process single point monitoring data separately, without considering the spatial correlation between points. In this paper, the Space-Time Kalman Filter (STKF), a dynamic spatio-temporal filtering model, is used as a spatio-tempora...

It is very important for dam safety control to identify reasonably dam behavior according to the prototypical observations on deformation, seepage, stress, etc. However, there are many cases in which the noise corrupts the prototypical observations, and it must be removed from the data. Considering the nonlinear and non-stationary characteristics of data series with signal intermittency, an ens...

Gastrointestinal transit times (GItts) were compared in separate litters of 10- and 15-day-old Sprague Dawley rats using barium sulphate. By tracking the leading front of the bolus on radiographs, the gastrocaecal transit times in pups were estimated. To measure the total GItt, the duration from orogastric gavage until an observable defecation of barium sulphate was recorded. The gastrocaecal t...

A decline in marine water quality entering the Great Barrier Reef (GBR) lagoon is associated with terrestrial runoff discharged from adjacent GBR catchments. Reef Plan 2013 outlines water quality targets to address this decline, with the eWater CRC Source Catchment modelling framework used to report progress towards meeting these targets. Catchment modelling is an ideal tool to investigate cons...

N6-Adenine methylation is an important epigenetic signal, which regulates various processes, such as DNA replication and repair and transcription. In gamma-proteobacteria, Dam is a stand-alone enzyme that methylates GATC sites, which are non-randomly distributed in the genome. Some of these overlap with transcription factor binding sites. This work describes a global computational analysis of a...

Resource managers are increasingly being challenged by stakeholder groups to consider dam removal as a policy option and as a tool for watershed management. As more dam owners face high maintenance costs, and rivers as spawning grounds for anadromous fish become increasingly valuable, dam removal may provide the greatest net benefit to society. This article reviews the impact of Endangered Spec...

Dam identification (DamID) is a powerful technique to generate genome-wide maps of chromatin protein binding. Due to its high sensitivity, it is particularly suited to study the genome interactions of chromatin proteins in small tissue samples in model organisms such as Drosophila Here, we report an intein-based approach to tune the expression level of Dam and Dam-fusion proteins in Drosophila ...

Desktop software agents are background processes that notify a computer user of certain predefined events. The complexity of desktop computing is increasing due to the proliferation of software agents. A desktop agent manager (DAM) may become an important component of desktop computing. This article focuses on the decision mechanism for the DAM to decide which agents should be allowed to access...

? ? Stop(k) Start(k) (k < 0) B(k) A(k) A(k) B(k) Stop(k) Start(k) Stop(k) Start(k) B(k) A(k) A(k) B(k) A(k) B(k) Stop(k) Start(k) Stop(k) Start(k) i; (i < 2) i; (2) Start(k) Stop(k) Start(k) Stop(k) B(k) A(k) B(k) A(k) A(k) B(k) i; (i<2) B(k) A(k) A(k) B(k) A(k) B(k) Stop(k) Start(k) Stop(k) Start(k) Fig. 2. HeNCE loop, fan, pipe, and conditional graph constructs.