In this white paper we provide a perspective on the opportunities and needs for data intensive science within the Department of Energy. In particular, we focus on two areas in which DOE’s landscape is different from those of other organizations. First, DOE is a leader in the use of high performance computing for modeling and simulation, and these computations generate huge amounts of data to ma...

We show that the singular sources in the energy-momentum tensor for the RandallSundrum brane world, viewed as a solution of type IIB supergravity, are composed of two elements. One of these is a D3-brane source with tension opposite in sign to the RS tension in five dimensions; the other arises from patching two regions of flat ten-dimensional spacetime. This resolves an apparent discrepancy be...

We surveyed 1351 residents who lived near six U.S. Department of Energy (DOE) former nuclear weapon sites using random digit dialing and stratified random sampling in order to determine which risks most worried them and the predictors of their worries. Respondents’ greatest concerns were threats to their drinking water, transportation accidents, and worker exposures. The strongest predictors of...

This paper presents the application of the sensitivity analysis techniques Design of Experiments (DOE) and metamodelling to the agent-based model AgriPoliS, which is a spatial and dynamic simulation model of regional structural change. DOE and metamodelling provide a more systematic analysis of results of complex simulation models. When summarising the results, it becomes clear that interest ra...

The Accelerated Model for Climate and Energy (ACME) is a leading-edge climate and Earth system model designed to address U.S. Department of Energy (DOE) mission needs. The ACME project involves collaboration between seven National Laboratories, the National Center for Atmospheric Research, four academic institutions, and one private-sector company. The ACME project funds ongoing efforts to ensu...

In this paper we report the results of coupled DOE-2 and 3D transient computational fluid dynamics (CFD) simulations for an unconditioned 100-year-old Buddhist temple, located in an urban area of Bangkok, Thailand. The HEATX CFD code was combined with the DOE-2 thermal simulation program, to analyze the heat transfer and airflow performance of the building. The indoor temperatures simulated by ...

Two-photon imaging has become a useful tool for optical monitoring of neural circuits, but it requires high laser power and serial scanning of each pixel in a sample. This results in slow imaging rates, limiting the measurements of fast signals such as neuronal activity. To improve the speed and signal-to-noise ratio of two-photon imaging, we introduce a simple modification of a two-photon micr...

Problems in design of technical systems can be solved by optimization or inventive solving principles. Two representation models are studied: Generalized System of Contradictions (GSC) as inventive principle and Design of Experience (DoE) as optimisation principle. Our purpose is to improve the capacity of design problems resolution by using the both solving principles articulated to one repres...

This research focused on using design of experiments (DoE) and simulation modeling to optimize the facility layout in a server assembly line, while introducing a new product. The critical factors that impact the performance metrics of cycle time, work-in-process and throughput were identified by using DoE principles. Subsequently, simulation modeling was used to evaluate the various what-if sce...

Combining the computational fluid dynamics (CFD) and the design of experiments (DOE) methods, as a mixed approach in modeling was proposed so that to simultaneously benefit from the advantages of both modeling methods. The presented method was validated using a coal hydraulic classifier in an industrial scale. Effects of operating parameters including feed flow rate, solid content and baffle le...