The clinical syndrome of anaesthetic-triggered malignant hyperpyrexia occurring in pigs is described. This condition in the pig is considered to be the same "explosive thermal idiosyncrasy" to general anaesthesia that is manifested by humans. The condition has a strong genetic factor occurring in 25 per cent of Landrace pigs used by us. Sex has no influence on its appearance. The clinical syndr...

The task of the anaesthetist is to control the continuum between consciousness and unconsciousness, pain and analgesia, muscle activity and relaxation—inhibition of activation and enhancement of inhibition.1 During an operation, an anaesthetized patient is part of a ‘feedback circuit’ (Figure 1). Changes in variables such as blood pressure and respiratory rate are monitored and stability is res...

A 9-month-old boy presented with a 1-day history of fever and croupy cough. He had been diagnosed with laryngomalacia at 4 months of age and treated for recurrent croup and bronchiolitis. He was <0.4th centile for weight. He had marked biphasic stridor in all positions along with tachypnoea. He showed some initial improvement with bronchodilators, steroids and antibiotics for suspected pneumoni...

To cite: Sotto Mayor J, Monteiro C, Shvets Y, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2016-216310 DESCRIPTION An 89-year-old man, with a history of thyroid papillary carcinoma with lymph node and skin metastasis, was admitted to the emergency department with deterioration of his general state and refusal to eat. The patient was without any other as...

A 22-year-old male patient presented with a fever for the previous 10 days, breathlessness with dry cough for the previous 3 days and decreased urine output since the morning of admission. His history was unremarkable. He denied any history of joint pain, rashes, eye symptoms, haemoptysis or sinus disease and there was no history of illicit drug abuse. He was a nonsmoker with no history of alco...

Acute bronchiolitis is the most common severe lower respiratory tract infection of infancy. About 2% of all babies born in the previous 12 months will be admitted to hospital with the condition.' Although the clinical picture can be produced by various viruses, including influenza and parainfluenza virus and the adenoviruses, most cases, particularly during the winter epidemics, are due to infe...

BACKGROUND Snakebite is a health issue specific to some parts of the world, especially in the tropical areas, where it produces many victims. The main clinical damage caused by snakebite involves haemotoxic, neurotoxic and myotoxic reactions. We report the case of a young woman suffering from snakebite who developed deep vein thrombosis and compartment syndrome. CASE REPORT We present the cas...

Among the causes of respiratory distress in infants and children must be included the interesting developmental anomalies of large arteries in the superior mediastinum. The tracheal compression which may result can cause respiratory disturbances such as dyspnoea, tachypnoea, and inspiratory retraction of the chest wall, as well as " wheeziness" or stridor. These disturbances are likely to be in...

To cite: Chattranukulchai P, Satitthummanid S, Puwanant S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013009861 DESCRIPTION A 63-year-old man with advanced lung cancer, suffered from increasing dyspnoea for 1 week. Physical findings included tachypnoea, decreased breath sound in the entire left chest. Chest film revealed complete ‘white out’ of left h...

Paraquat is a bipyridylium non-selective contact herbicide commonly used worldwide. When ingestion occurs by humans and animals either accidentally, intentionally or maliciously, paraquat selectively accumulates in the lungs resulting in the production of oxygen-free radicals, causing membrane damage and cell death. Intoxicated subjects typically show progressive and fatal pulmonary haemorrhage...