How ER stress gives cells the CHOP L i et al. explain how prolonged stress sparks the endoplasmic reticulum (ER) to release its calcium stores, inducing cells to undergo apoptosis in several aging-related diseases. Stressful conditions cause misfolded proteins to accumulate in the ER. Cells try to recover by slowing down translation and increasing production of their protein folding machinery. ...

Due to increasing importance of desertification challenges and its consequences the necessity of sustainabledevelopment achievement in arid and semi-arid regions is essential in order to avoid limited sources asting, increase the efficiency of controlling, reclamation and restoration projects of natural areas. Based on the iterature review, it has been recognized that combating desertification ...

Bagh Vang Section is located at about 45 km to the Northwest of Tabas and South of Shirgesht areas. In Bagh Vang Section, the Permian deposits of the Jamal Formation with a thickness of 270 m are underlain by the Sardar Formation disconformably. The formation is also transitionally and conformably overlain by Lower Triassic deposits of Sorkh Shale Formation. A total of 124 rock samples have bee...

There are various criteria that need to be examined alongside each other when designing a longwall mining system. Challenges such as determination of the supported roof width, support system design, caving height determination, lateral or chain pillar size determination, and optimum support design for the main gate and tail gate roadways have to be tackled for this aim. Three-dimensional analys...

Performance of structures during recent earthquakes shows that the effect of vertical component of earthquake (VCE) could be considered as one of the main causes of bridges collapse. In most of bridge design codes, for seismic analysis of bridges, VCE is not taken into account or a distinguished method isn’t presented for assessment of VCE. In the present work, the effect of VCE on two existing...

bagh vang section is located at about 45 km to the northwest of tabas and south of shirgesht areas. in bagh vang section, the permian deposits of the jamal formation with a thickness of 270 m are underlain by the sardar formation disconformably. the formation is also transitionally and conformably overlain by lower triassic deposits of sorkh shale formation. a total of 124 rock samples have bee...

due to increasing importance of desertification challenges and its consequences the necessity of sustainabledevelopment achievement in arid and semi-arid regions is essential in order to avoid limited sources asting, increase the efficiency of controlling, reclamation and restoration projects of natural areas. based on the iterature review, it has been recognized that combating desertification ...

In the present study, an investigation was carried out on Parvadeh coal mine in Tabas, Iran, to survey the effect of fractures on unusual methane gas emission in coal mines. This coal mine was chosen for investigating because of its high methane gas content in the coal body and available data from sensors in desired locations. Gas concentration monitoring programs were carried out at the mine s...