Human cardiac actin mutants E99K and A230V were expressed with baculovirus/insect cells and used to reconstitute the thin-filament of bovine cardiac (BVC) muscle fibers, together with tropomyosin (Tm) and troponin (Tn) purified from bovine ventricles. Effects of [Ca(2+)], [ATP], and [phosphate] on tension and its transients were studied at 25°C. In the absence of Tm/Tn, both mutants significant...

with given a, b, t0, t1 and n ≥ 0. This sequence was introduced by Horadam [3] in 1965, and it generalizes many sequences (see [1, 4]). Examples of such sequences are Fibonacci polynomials sequence (Fn(x))n≥0, Lucas polynomials sequence (Ln(x))n≥0, and Pell polynomials sequence (Pn(x))n≥0, when one has a = x, b = t1 = 1, t0 = 0; a = t1 = x, b = 1, t0 = 2; and a = 2x, b = t1 = 1, t0 = 0; respect...

This paper studies divisibility properties of sequences defined inductively by n,=l, a n+1 =Sa,+tLea,], where s, t are integers, and 0 is a quadratic irrationality. Under appropriate hypotheses (especially that s + t0 be a PV-number) it is proved that the highest power of A that divides a,, where A is the discriminant of 19, tends to infinity. This is noteworthy in that truncation would normall...

Let Ω be a pseudoconvex domain with C-smooth boundary in CP. We prove that the ∂̄-Neumann operator N exists for (p, q)-forms on Ω. Furthermore, there exists a t0 > 0 such that the operators N , ∂̄N , ∂̄N and the Bergman projection are regular in the Sobolev space W (Ω̄) for t < t0. The boundary estimates above have applications in complex geometry. We use the estimates to prove the nonexistence of ...

and Applied Analysis 3 where m ∈ N, α is the quotient of odd positive integers, t0 ∈ T, the time scale interval t0,∞ T {t ∈ T : t ≥ t0}, a ∈ Crd t0,∞ T, 0,∞ , p ∈ C t0,∞ T,R , τ, δ ∈ C T,T with limt→∞τ t limt→∞δ t ∞ and f ∈ C t0,∞ T×R,R satisfying the following conditions: i uf t, u > 0 for any t ∈ t0,∞ T and u/ 0. ii f t, u is nondecreasing in u for any t ∈ t0,∞ T. Since we are interested in t...

PURPOSE Advanced hemodynamic monitoring in cardiac surgery translates into improvement in outcomes. We evaluated the relationship between central venous (ScvO2) and mixed venous (SvO2) saturations over the early postoperative period. The adequacy of their interchangeability was tested in patients with varying degrees of cardiac performance. METHODS In this prospective observational study, we ...

Variations of intracellular concentrations of isocitrate and NADP+ were measured throughout all growth phases of the marine bacterium Pseudomonas nautica. The intracellular isocitrate concentration tracked the intracellular protein concentration throughout all phases of growth. It rapidly increased in early exponential phase to a maximum and fell to nearly zero in parallel with pyruvate exhaust...

We propose a new cosmological model with a time-dependent cosmological constant (Λ ∝ 1/t), which starting at the Planck time as ΛP l ∼ M P l, evolves to the present-day allowed value of Λ0 ∼ 10M P l. This scenario is supported by non-critical string theory considerations. We compute the age of the Universe and the time-dependence of the scale factor in this model, and find general agreement wit...