Colorectal cancer is the second leading cause of mortality from cancer in the United States. Death from colorectal cancer usually results from metastatic disease to the liver. Complete surgical resection is the only potentially curative treatment option for metastatic colorectal cancer to the liver, with a five-year survival rate of approximately 30%-40%. The addition of adjuvant systemic or he...

normal 0 false false false en-us x-none ar-sa anaplastic thyroid cancer (atc) is a rare disease with an incidence of less than three cases per million of habitants in western countries. atc accounts for 1‑10% of all tumors derived from the thyroid gland. classic chemotherapy approach based on platinum and anthracyclines regimens have been considered standard for the last decades. novel multit...

Patients with Stage IV cholangiocarcinoma are currently not considered to be surgical candidates and are typically offered systemic chemotherapy. Recently, several novel systemic chemotherapy regimens have allowed an initially unresectable cholangiocarcinoma to be resectable. The aim of this article is to present the usefulness of adjuvant surgery in a case of advanced cholangiocarcinoma that w...

BACKGROUND Radical cystectomy is the standard of care for patients with localized muscle-invasive bladder cancer; however, 50 percent of patients still relapse in distant sites following surgery. A systemic approach is needed to improve outcomes in bladder cancer in the metastatic and perioperative settings. METHODS We reviewed the literature for use of systemic chemotherapy in bladder cancer...

RATIONALE Endobronchial ultrasound as a powerful diagnostic technology can also be used to perform intratumoral chemotherapy for extraluminal tumor. PATIENT CONCERNS A 69-year-old man with chronic obstructive pulmonary disease (COPD) presented with worsening dyspnea. A pulmonary function test showed severe airway obstruction and that forced expiratory volume in 1 s was 43% of the predicted va...

here, we describe young men with synovial sarcoma in the palatine tonsil, who presented with a 3-4 month history of progressive sore throat, tonsillar ulcerative mass and bleeding. clinical and radiological examinations revealed that the tumors arose from the palatine tonsil and extended to the parapharyngeal space. both tumors were too advanced to remove completely; therefore, they underwent s...

Objective: This study aimed to evaluate the variation and importance of certain hematological, enzymatic, oxidative stress markers in women with breast cancer under chemotherapy treatment. Methods: The comprised forty histopathologically proven female patients at Omega Cancer Hospital Visakhapatnam. All subjects were divided into four groups: a control group 40 healthy females similar age, (bef...

background: inherent toxicity of cytotoxic drugs is the basis for their potential adverse risks from occupational exposure to the nursing staff. in iran, chemotherapy regimens are prescribed and administered according to the world updated protocols. but little is done regarding the protective standards in this field. methods: an observational cross-sectional survey was conducted among nurses wh...

With regard to resectable disease, two recent phase III randomized trials showed that postoperative chemotherapy, either 5fluorouracil or gemcitabine, significantly prolongs overall and disease-free survival with respect to observation alone [1, 2]. A Radiation Therapy Oncology Group (RTOG) phase III randomized trial showed significantly better survival after gemcitabine chemotherapy with respe...

Background and Objectives. Systemic chemotherapy administered prior to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal mucinous adenocarcinoma of appendiceal origin (PMCA) is associated with a significant rate of histological response. The impact of preoperative systemic chemotherapy (PSC) on intraperitoneal tumor burden, completeness of cytoreduction,...