Urinary tract obstruction leads to obstructive nephropathy, which in turn, frequently results in renal failure. Congenital urinary tract obstruction can be traced back to errors during the organogenesis of the urinary system. A fundamental understanding of the causes of urinary tract obstruction and the developmental processes involved are critical for improving the diagnostic and therapeutic s...

Little is known about prenatal and perinatal brain injury resulting in subsequent clumsy behavior in children. One candidate motor system is the pyramidal tract. The tract traverses the entire central nervous system and, through direct and indirect connections to the brainstem and spinal cord sensory and motor nuclei, is involved in the learning and execution of skilled movements. Here, rats, e...

Multisubject statistical analyses of diffusion tensor images in regions of specific white matter tracts have commonly measured only the mean value of a scalar invariant such as the fractional anisotropy (FA), ignoring the spatial variation of FA along the length of fiber tracts. We propose to instead perform tract-based morphometry (TBM), or the statistical analysis of diffusion MRI data in an ...

To investigate the role of tenascin-R in nervous system development, we studied axon pathfinding in the developing optic system of zebrafish. Zebrafish tenascin-R has the same domain structure as tenascin-R in amniotes. Amino acid sequence identity with human tenascin-R is 60%. In 3-d-old larvae, tenascin-R mRNA is expressed in scattered cells throughout the periventricular cell layer of the di...

background and objectives: urinary tract infections (uti) are one of the most common infectious diseases with different microbial agent and antimicrobial resistant pattern in hospitalized patients and outpatients. in order to assess the adequacy of therapy, knowledge of prevalence and resistance pattern of the bacteria is necessary. the main aim of this study was to evaluate the prevalence and ...

background a considerable portion of gastrointestinal malignancies undergoes surgery without curative resection. this study was conducted to assess surgical outcome in patients with gastrointestinal cancers. methods we reviewed individuals with esophagus, stomach, colon and rectum cancers admitted for surgical treatment after initial preoperative evaluations. surgical outcome, stage of tumors a...

conclusions it was demonstrated that, considerable percentage of uti existed in the gastroenteritis diseases. early treatment of uti in patients would reduce uti complications. objectives the current study aimed to investigate uti in patients with diarrhea. patients and methods this case-control study was conducted on 200 participants, 100 were patients with acute gastroenteritis and the other ...

the gastrointestinal tract is the most frequently involved extranodal location for malt* lymphomas, but malt lymphomas of the large intestine are rarely observed. a treatment for colorectal malt lymphoma has not yet been established. in colonic malt lymphomas, the literature suggests that surgical resection of localized lesion may be the best choice. in the present case, combination of multi-ag...

background: endoscopy of the upper gastrointestinal tract is the most accurate method for the diagnosis of most disease conditions associated with dyspepsia. however, endoscopy involves some discomfort, significant social inconvenience, and cost. attempts to identify those patients most likely to benefit from endoscopy have met with variable success. to evaluate endoscopic findings of the upper...