A new automated method to reliably quantify reticulated platelets, expressed as the immature platelet fraction (IPF), has been developed utilizing the XE-2100 blood cell counter with upgraded software (Sysmex, Kobe, Japan). The IPF is identified by flow cytometry techniques and the use of a nucleic acid specific dye in the reticulocyte/optical platelet channel. The clinical utility of this para...

Dear Sir, Activated platelets play a crucial role in the pathogenesis of acute coronary syndrome (ACS) (1), and platelet size can be a determinant of platelet function. Thus, large platelets are metabolically more active than small platelets and have greater pro-thrombotic potential (2). However, the clinical influence of platelet size, measured as mean platelet volume (MPV), is controversial (...

Mastitis is one of the most serious and costly diseases affecting dairy cattle production. In the present study, effects of a lactoferrin gene polymorphism (intron 6) on milk somatic cell count (SCC) and subclinical mastitis was investigated in 121 Holstein dairy cattle. Two alleles of A and B and two genotypes of AA and AB were found in an EcoRI recognized single nucleotide polymorphism in int...

BACKGROUND Several point-of-care (POC) tests are available for evaluation of febrile patients, but the data about their performance in acute care setting is sparse. We investigated the analytical accuracy and feasibility of POC tests for white blood cell (WBC) count and C-reactive protein (CRP) at the pediatric emergency department (ED). METHODS In the first part of the study, HemoCue WBC and...

In 2008, the World Health Organization (WHO) introduced a new hematological neoplasm category; myelodysplastic/myeloproliferative neoplasms (MDS/MPN), which included four main subcategories. This disease is often misdiagnosed, which delays effective therapy. The present study evaluated the role of routine blood examinations and morphological analysis of peripheral blood cells in the reliable di...

INTRODUCTION The immature platelet and immature reticulocyte fractions represent the ratios of platelets and reticulocytes recently released into the circulation and thus with higher RNA content. They are considered early indicators of bone marrow recovery. OBJECTIVE The aim of this study was to determine the reference ranges for the immature platelet and reticulocyte fractions of hematologic...

BACKGROUND Recurrent aphthous stomatitis (RAS) is the most common inflammatory ulcerative condition of oral cavity. The aim of this study was to compare the levels of the salivary Malondialdehyde (MDA) and total antioxidant capacity (TAC) and blood parameter in RAS versus healthy controls. METHODS This case-control study consisted of 28 patients with RAS and 28 age and sex -matched control wi...

Complete blood count (CBC), important information about the volume, number of cells and components of blood cells could diagnose of many diseases provided. In patients Infected with invasive pulmonary fungal disease (IFD) some of the changes in them occurs, blood index somewhat warning and of them can be used to diagnose the treatment of disease.The study was cross-sectional. In this study, 26 ...

Parasitic infections continue to take their toll on HIV positive patients by influencing the blood qualitatively and quantitatively. The objective of this study was to determine the prevalence of intestinal parasitic infections in relation to anaemia and CD4 counts among HIV-infected patients in Benin City, Nigeria. Using a serial sampling method, a total of 2000 HIV-infected patients were recr...

Objective: To find out different changes in the peripheral blood of patients suffering from Malaria. Material and Methods: It was a descriptive case series study conducted in pathology department of KMC/KTH from May 2013 to May 2014. A total of 200 Malarial patients were subjected to complete blood counts performed in automated Haematology analyzer, Sysmex KX 21 and thick and thin blood films s...