Abstract Deafness, the most frequent sensory deficit in humans, is extremely heterogeneous with hundreds of genes involved. Clinical and genetic analyses an extended consanguineous family pre-lingual, moderate-to-profound autosomal recessive sensorineural hearing loss, allowed us to identify CLRN2, encoding a tetraspan protein, as new deafness gene. Homozygosity mapping followed by exome sequen...

Hearing loss may place a heavy burden on the patient and patient's family. Given the high incidence of hearing loss among newborns and the huge cost of treatment and care (including cochlear implantation), prenatal diagnosis is strongly recommended. Termination of the fetus may be considered as an extreme outcome to the discovery of a potential deaf fetus, and therefore preimplantation genetic ...

background: taxi drivers have the most important role in the public transport services. they are exposed to various harmful agents and occupational hazards. noise is a harmful occupational factors and hearing loss is its most important effect. protection of drivers against hearing loss is essential. this study was performed to determine the prevalence of hearing loss among taxi and agency drive...