Sagittal MR imaging was used to investigate cerebral sulci bordering the functionally important areas on the lateral suprasylvian surface. The aim of the study was to identify characteristic relationships of the inferior precentral sulcus to nearby sulci and gyri. MR findings in 20 healthy volunteers were compared with those in 62 intact postmortem hemispheres. MR techniques are described for t...

The pars triangular is a portion of Broca's area. The convolutions that form the inferior and caudal extent of the pars triangularis include the anterior horizontal and anterior ascending rami of the sylvian fissure, respectively. To learn if there are anatomic asymmetries of the pars triangularis, these convolutions were measured on volumetric magnetic resonance imaging scans of 11 patients wh...

Magnetoencephalographic (MEG) responses of both auditory cortices to simple auditory stimuli presented monaurally to either ear were recorded from a single subject. A distributed current model and a current dipole model were used to analyse the responses at the latency of the dominant N1m complex. At the N1m the current density was localised to a single area and was consequently well modelled b...

While widely distributed, the vascular supply of the brain is particularly prominent in certain anatomical structures because of the high vessel density or their large size. A digital atlas of middle to large vessels in Montreal Neurological Institute (MNI) coordinates is here presented, obtained from a sample of N = 38 healthy participants scanned with the time-of-flight (TOF) magnetic resonan...

We recorded electrophysiological responses from the left frontal and temporal cortex of awake neurosurgical patients to both repetitive background and rare deviant auditory stimuli. Prominent sensory event-related potentials (ERPs) were recorded from auditory association cortex of the temporal lobe and adjacent regions surrounding the posterior Sylvian fissure. Deviant stimuli generated an addi...

The human neocortex has numerous specialized functional areas whose formation is poorly understood. Here, we describe a 15-base pair deletion mutation in a regulatory element of GPR56 that selectively disrupts human cortex surrounding the Sylvian fissure bilaterally including "Broca's area," the primary language area, by disrupting regional GPR56 expression and blocking RFX transcription factor...

The structure of the sources underlying surface recordings of brain activity is very complex. We have developed an iterative procedure based on independent component analysis to obtain single-trial estimates of the auditory N100 component recorded in normal subjects using a pure tone, binaural stimulation task and a wholehead, 256-channel recording system. For each channel, the processed single...

A 57 year old female presented with acute onset headache started from 1 month before the current visit. The headache was located on the left frontotemporal area and had increased during the month. On brain CT scan, there were bilateral round hyperdense lesions in the sylvian fissure which were flow void on brain MRI indicating aneurysms. Brain DSA (digital subtraction angiography) was performed...

A 52-year-old right handed man presented with medically intractable partial seizures consisting of numbness on the left upper back spreading to the left upper as well as lower limbs. Head computed tomography and magnetic resonance imaging showed a round calcified lesion in the depth of the superior ramus of the right sylvian fissure. Ictal electrocorticographic recording with chronically implan...