UNLABELLED MRI offers perfect visualization of spondylotic stenosis of the cervical spine, but morphologic imaging does not correlate with clinical symptoms and postoperative recovery after decompression surgery. In this prospective study, we investigated the role of (18)F-FDG PET in patients with degenerative stenosis of the cervical spinal cord in relation to postsurgical outcome. METHODS T...

PURPOSE We investigated the usability of standardized uptake values (SUV) obtained from both two- and three-dimensional (2D and 3D) positron-emission tomography and computed tomography (PET-CT) imaging, and compared the images obtained from these techniques in terms of image quality, lesion detectability, and the presence of artifacts. MATERIALS AND METHODS Image data from 100 patients, who h...

Positron emission tomography (PET) using F-18 fluorodeoxyglucose (FDG) was performed in non-Hodgkin's lymphoma (NHL), which is known to be highly responsive to chemotherapy, but also yields variable treatment results to answer the following questions: (1) What is the extent and time course of changes in FDG utilization in response to chemotherapy? (2) Are the changes of FDG uptake at early time...

Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, NY, NY, USA Current MR/PET systems employ segmentation of MR images and subsequent assignment of empirical attenuation map values for quantitative PET reconstruction. In this current study we examine the quantitative differences between our carotid artery imaging protocol on both a PET/CT and an MR/PET scann...

Background: The prognostic factors for breast cancer include pretreatment staging, nodal and distant metastasis, hormone receptor status, ki67 index, molecular subtype. For adequate treatment, [18F]FDG PET/CT is now being used to prognosticate the course response of treatment in patients. Our study aims find association between metabolic activity primary tumors as SUV uptake such ER/PgR/Her2neu...

Abstract Background Diagnosis of tumour thrombosis and differentiating it from benign are essential for managing patients, planning treatments, minimising unneeded anticoagulation therapy. Bland thrombi occur in both cancer non-cancer patients; bland can coexist. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F - FDG PET/CT) is useful detecting diagnosing distinguish...

BACKGROUND Delineation of glioma extent for surgical or radiotherapy planning is routinely based on MRI. There is increasing awareness that contrast enhancement on T1-weighted images (T1-CE) may not reflect the entire extent of disease. The amino acid tracer (18)F-DOPA (3,4-dihydroxy-6-[18F] fluoro-l-phenylalanine) has a high tumor-to-background signal and high sensitivity for glioma imaging. T...

Castleman's disease is a benign lymphoproliferative disease characterised by hyperplasia of lymphoid follicles. It can affect any lymph nodes in the body. Here we describe a caucasian patient who presented with six months history of shortness of breath with CT scan confirming an 8 cm segment of consolidated lung in left hilum. PET scan revealed a mass measuring 68x80x55 mm extending from the le...

UNLABELLED PET with L-1-(11)C-tyrosine (TYR) can measure and quantify increased protein synthesis in tumor tissue in vivo. For quantification of the protein synthesis rate (PSR), arterial cannulation with repeated blood sampling to obtain the plasma input function and a dynamic TYR PET study to calculate a time-activity curve are necessary. In most PET studies the standardized uptake value (SUV...