نتایج جستجو برای: survival analyses
تعداد نتایج: 697213 فیلتر نتایج به سال:
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PURPOSE PFS is often used as a surrogate endpoint for OS in metastatic breast cancer studies. We have evaluated the association of treatment effect on PFS with significant HROS (and how this association is affected by other factors) in published prospective metastatic breast cancer studies. METHODS A systematic literature search in PubMed identified prospective metastatic breast cancer studie...
We assessed the value of palliative local treatment of incurable metastatic lesions in colorectal cancer patients. Consecutive patients with metastatic colorectal cancer treated between 2003 and 2014 were retrospectively reviewed. Propensity score matching was used to create comparable palliative local treatment and chemotherapy alone groups (n = 272 in each group). The primary endpoint was ove...
The association between an area-based measure of deprivation and survival from the 10 most common cancers was studied in 155,682 patients diagnosed between 1980 and 1989 in the area covered by the South Thames Regional Health Authority. Furthermore, the impact of stage of disease at diagnosis on this association was studied. The measure of deprivation was the Carstairs Index of the census enume...
Abstract Glioblastomas are the most common primary malignant brain tumor in adults. Subject age is a strong prognostic factor for survival. We performed co-morbidity analysis of younger vs. older (greater than 65 years) adults with grade IV gliomas (GIV) to understand inherent differences that vary subject age. Electronic health records 1,208 GIV patients were collected at single center between...
Introduction The use of inconsistent and outdated information may significantly compromise healthcare decision-making. We aimed to assess the extent lag times in publication indexing network meta-analyses (NMAs). Methods Searches for NMAs on drug interventions were performed PubMed (May 2020). Lag measured as time between last systematic search date article's submission, acceptance, online publ...
Background and Aim: Recent advances in molecular and cellular biology and the importance of Epidermal growth factor receptor(EGFR) in the development and progression of many solid malignancies such as Colorectal Cancer (CRC) and non- small cell lung cancer have allowed rapid advances in rational drug design and targeted therapies for malignancies.Cetuximab or Erbitux, an IgG1 monoclonal antib...
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