Human T-lymphotropic virus 1 (HTLV-1) has infected human beings for thousands of years, but knowledge about the infection and its pathogenesis is only recently emerging. The virus can be transmitted from mother to child, through sexual contact, and through contaminated blood products. There are areas in Japan, sub-Saharan Africa, the Caribbean, and South America where more than 1% of the genera...

Prolonged separation from parents has been shown to be significantly related to psychiatric morbidity in children. The relative role of mother and father in the socio-emotional development of the child has been variously contested. A controlled retrospective study on children with well defined hysterical, emotional and conduct disorder was done for experiences of separation from parents between...

The technique of surrogate data has been used as a method to test for membership of particular classes of linear systems. We suggest an obvious extension of this to classes of nonlinear parametric models and demonstrate our methods with respiratory data from sleeping human infants. Although our data are clearly distinct from the different classes of linear systems we are unable to distinguish b...

Various assisted reproductive techniques have been developed and refined to obtain a large number of offspring from genetically superior animals or obtain offspring from infertile (or subfertile) animals. The embryo transfer is one assisted reproductive technique developed well, aimed at increased productivity of selected females, disease control, importation and exportation of livestock, rapid...

In utero hematopoietic cell transplantation (IUHCT) has been performed in Mucopolysaccharidosis Type VII (MPSVII) mice, but a lifelong engraftment of allogeneic donor cells has not been achieved. In this study, we sought to confirm a lifelong engraftment of allogeneic donor cells immunologically matched to the mother and to achieve partial rescue of phenotypes in the original MPSVII strain thro...

IKE THE MISSISSIPPI RIVER FOLLOWING THE SPRING SNOW MELT, THE FAMILY landscape is being flooded with new technologies having to do with baby making or not making. The explosion of progress in reproductive technologies is creating choice in a dimension of life we previously consigned to destiny, namely, procreating children. Fertile women can stop baby making with Norplant, RU486, or abortion. I...

It has been a common claim that surrogacy is morally problematic since it involves harm to the child or the surrogate-the harm argument. Due to a growing body of empirical research, the harm argument has seen a decrease in popularity, as there seems to be little evidence of harmful consequences of surrogacy. In this article, two revised versions of the harm argument are developed. It is argued ...

BACKGROUND It is clear that the structure and function of the human microbiota has significant impact on maintenance of health and yet the factors that give rise to an adult microbiota are poorly understood. A combination of genetics, diet, environment, and life history are all thought to impact the development of the gut microbiome. Here we study a chronosequence of the gut microbiota found in...

Various assisted reproductive techniques have been developed and refined to obtain a large number of offspring from genetically superior animals or obtain offspring from infertile (or subfertile) animals. The embryo transfer is one assisted reproductive technique developed well, aimed at increased productivity of selected females, disease control, importation and exportation of livestock, rapid...

The mechanisms for provisioning maternal resources to offspring in placental mammals involve complex interactions between maternally regulated and fetally regulated gene networks in the placenta, a tissue that is derived from the zygote and therefore of fetal origin. Here we describe a novel use of an embryo transfer system in mice to identify gene networks in the placenta that are regulated by...