OBJECTIVE To investigate the efficacy and safety of dietary supplements for patients with osteoarthritis. DESIGN An intervention systematic review with random effects meta-analysis and meta-regression. DATA SOURCES MEDLINE, EMBASE, Cochrane Register of Controlled Trials, Allied and Complementary Medicine and Cumulative Index to Nursing and Allied Health Literature were searched from incepti...

BACKGROUND Increased requirement and decreased dietary intakes of micronutrients during pregnancy might affect maternal health and pregnancy outcomes. This study was aimed to examine the effects of two types of multiple micronutrient supplementations on pregnancy outcomes in Kashan, Iran. METHODS In a randomized single-blind controlled clinical trial, 104 primigravid singleton pregnant women ...

OBJECTIVE To assess dietary supplement use and its association with micronutrient intakes and adequacy among 2,195 US men and women aged 40 to 59 years from eight diverse population samples surveyed by the International Population Study on Macronutrients and Blood Pressure. DESIGN Four 24-hour dietary recalls were collected, including information on dietary supplements. The Nutrition Data Sys...

BACKGROUND As defined by the Dietary Supplement Health and Education Act 1997, such substances as herbs and dietary supplements fall under general Food and Drug Administration supervision but have not been closely regulated to date. We examined the thyroid hormone content in readily available dietary health supplements marketed for "thyroid support." METHODS Ten commercially available thyroid...

As stated in the foreword (1) to articles by Henriquez-Sanchez et al. (2) and others, this collection presents valuable work that identifies quality features of dietary validation studies and supports the use of FFQ in future research. The authors' substantial effort and results are appreciated; however, inconsistencies in classifying studies as including supplements, assigning quality scores a...