Quantitative proteomic profiling using liquid chromatography-mass spectrometry is emerging as an important tool for biomarker discovery, prompting development of algorithms for high-throughput peptide feature detection in complex samples. However, neither annotated standard data sets nor quality control metrics currently exist for assessing the validity of feature detection algorithms. We propo...

The purpose of this study was to address two methodological issues that have called into question whether previously reported gene-environment interaction (GxE) effects for adolescent alcohol use are 'real'. These issues are (1) the potential correlation between the environmental moderator and the outcome across twins and (2) non-linear transformations of the behavioral outcome. Three environme...

BACKGROUND Research suggests that substance abusers make more disadvantageous decisions on the simulated gambling task (SGT); such decisions are associated with deviance proneness and antisocial symptoms. This study examines decision making on the SGT in young adults with alcohol dependence who are treatment-naive (TxN). METHODS A total of 116 subjects (58 controls, 58 TxNs) were tested on th...

When including clinical mastitis in the breeding goal, it is useful to know what measure of the trait is most appropriate and its relationship to the primary production traits and indicator traits in the relevant population. In this paper, genetic and phenotypic parameters for clinical mastitis, somatic cell production deviance, and protein yield were estimated for the dairy breed Danish Red. I...

Risk behaviors such as substance use or deviance are often limited to the early stages of the life course. Whereas the onset of risk behavior is well studied, less is currently known about the decline and timing of cessation of risk behaviors of different domains during young adulthood. Prevalence and longitudinal developmental patterning of alcohol use, drinking to the point of drunkenness, sm...

Deviance is a fundamental social construct because the members of society interpret its meaning and attribute to it. In our research we described causes that determine deviance (juvenile delinquency): internal/individual external / causes. The purpose was make comparison between psychological problems institutionalized adolescents with deviant behaviour those non-institutionalized behaviour.

Migration is a key process for spatially structured populations. We examined how a variety of patch based metrics commonly used to predict the number of immigrants to a habitat patch performed based on data from three different years, in two distinct insect systems. The first system was an herbivorous beetle inhabiting patches of its host plant within a ‘typical’ patch network. In this system t...

High-quality surface reconstruction of scanned physical objects using CAD or polygonal modeling packages represents a time consuming manual process. So far none of the fully automatic approaches to reconstruct free-from surfaces have lead to satisfying results that can compete with manually created objects based on traditional modeling techniques and most importantly an artist’s experience. In ...

abstract background: supervisors should have certain characteristics and adequate preparation for their roles. yet, there are no well‑educated experts knowing about the supervisor’s role and responsibilities and how to train them. so, this research was conducted with the purpose of finding the factors affecting nursing supervisor training. materials and methods: this research is an inductive co...