A 75-year-old patient was evaluated for dementia. His past medical history included an ischaemic cardiomyopathy treated with aspirin daily. His neurological examination showed mild ataxia syndrome and central deafness. The neuropsychological examination did not suggest Alzheimer's disease. No specific aetiology was found from biological investigations, but MRI scans revealed a superficial sider...

Howard H. Feldman, Luis F. Maia, Ian R.A. Mackenzie, Bruce B. Forster, Jeff Angiopathy in Alzheimer Disease Superficial Siderosis : A Potential Diagnostic Marker of Cerebral Amyloid ISSN: 1524-4628 Copyright © 2008 American Heart Association. All rights reserved. Print ISSN: 0039-2499. Online Stroke is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX 72514 doi: 10...

BACKGROUND Chronically increased intestinal iron uptake in genetic hemochromatosis (HC) may cause organ failure. Whilst iron loading from blood transfusions may cause dilated cardiomyopathy in conditions such as thalassemia, the in-vivo prevalence of myocardial siderosis in HC is unclear, and its relation to left ventricular (LV) dysfunction is controversial. Most previous data on myocardial si...

Abstract Superficial Siderosis of the Central Nervous System (SSCNS) is a condition secondary to deposition hemosiderin within subpial layers central nervous system leading its progressive degeneration, clinically responsible for hearing impairment, cerebellar ataxia and pyramidal syndrome. Here we report case 61-year-old man with medical history congenital hemophilia A presenting typical clini...