نتایج جستجو برای: sulfonic acid based precursors sap

تعداد نتایج: 3621907  

Journal: :Molecules 2013
Duckhee Lee

Sulfonated carbonaceous material useful as a solid acid catalyst was prepared from lignosulfonate, a waste of the paper-making industry sulfite pulping process, and characterized by 13C-NMR, FT-IR, TGA, SEM and elemental analysis, etc. The sulfonic acid group density and total density of all acid groups in the sulfonated carbonaceous material was determined by titration to be 1.24 mmol/g and 5....

Journal: :Environmental toxicology and chemistry 2003
Paul D Jones Wenyue Hu Wim De Coen John L Newsted John P Giesy

Perfluorooctane sulfonic acid (PFOS) accumulates in the liver and blood of exposed organisms. The potential for these surfactant molecules to interfere with hormone/protein interactions in blood is of concern given the importance of these interactions. The PFOS binding to serum proteins was investigated by assessing its ability to displace a variety of steroid hormones from specific binding pro...

Journal: :Organic & biomolecular chemistry 2006
Takehisa Yane Hideyuki Shinmori Toshifumi Takeuchi

Molecularly imprinted polymers bearing atrazine transforming activity were prepared by using newly designed templates that are atrazine analogues attached with an allyl or a styryl group via a disulfide bond at the 6-position, methacrylic acid as a functional monomer and styrene/divinylbenzene as crosslinkers. After polymerization, the disulfide bond was reduced to remove the atrazine moiety fr...

2014
Mohammed Q Khan Ali Alaraj Fahad Alsohaibani Khalid Al-Kahtani Sahar Jbarah Hamad Al-Ashgar

BACKGROUND/AIMS Approximately one-third of non-erosive reflux disease (NERD) patients are refractory to proton pump inhibitors (PPI) and face a therapeutic challenge. Therefore, it is important to differentiate between pathological and non-pathological reflux utilizing multichannel intraluminal impedance-pH (MII-pH) to analyze symptom-reflux association and diagnose true NERD versus hyper-sensi...

2012
Nan Wang Ronghua Wang Xia Shi Gang Zou

A clean process has been developed for the synthesis of 2-adamantylphenol derivatives through adamantylation of substituted phenols with adamantanols catalyzed by commercially available and recyclable ion-exchange sulfonic acid resin in acetic acid. The sole byproduct of the adamantylation reaction, namely water, could be converted into the solvent acetic acid by addition of a slight excess of ...

Journal: :Science translational medicine 2018
Duncan B Richards Louise M Cookson Sharon V Barton Lia Liefaard Thirusha Lane David F Hutt James M Ritter Marianna Fontana James C Moon Julian D Gillmore Ashutosh Wechalekar Philip N Hawkins Mark B Pepys

Systemic amyloidosis is a fatal disorder caused by pathological extracellular deposits of amyloid fibrils that are always coated with the normal plasma protein, serum amyloid P component (SAP). The small-molecule drug, miridesap, [(R)-1-[6-[(R)-2-carboxy-pyrrolidin-1-yl]-6-oxo-hexanoyl]pyrrolidine-2-carboxylic acid (CPHPC)] depletes circulating SAP but leaves some SAP in amyloid deposits. This ...

2013
Emma R. Job Barbara Bottazzi Brad Gilbertson Kathryn M. Edenborough Lorena E. Brown Alberto Mantovani Andrew G. Brooks Patrick C. Reading

Members of the pentraxin family, including PTX3 and serum amyloid P component (SAP), have been reported to play a role in innate host defence against a range of microbial pathogens, yet little is known regarding their antiviral activities. In this study, we demonstrate that human SAP binds to human influenza A virus (IAV) strains and mediates a range of antiviral activities, including inhibitio...

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