نتایج جستجو برای: suicide gene
تعداد نتایج: 1164769 فیلتر نتایج به سال:
Background Numerous studies have reported associations between the brain-derived neurotrophic factor (BDNF) gene and psychiatric disorders, including suicidal behavior, although with conflicting results. Methods A total of 250 major depressive disorder patients were collected in the context of a European multicenter resistant depression study and treated with antidepressants at adequate doses...
background : hamadan is a province with high incidence rate of suicide. the present study was conducted to assess suicide and its associated risk factors in this province. methods : in this cross-sectional study, all cases of suicide occurred in the province, were investigated from april 2008 to march 2010. the data were collected from provincial health center and forensic medicine's databases ...
Brain oxysterol levels, which are enzymatic oxidation products of cholesterol (Chl), have been proposed to reflect the dynamic process of physiological synapse maintenance and repair of nerve terminals within the central nervous system (CNS), due to the turnover of membrane Chl. Modifications of oxysterols have important implications in neurological conditions, especially in neurodegenerative a...
Suicide is a serious public health issue that results from an interaction between multiple risk factors including individual vulnerabilities to complex feelings of hopelessness, fear, and stress. Although kinase genes have been implicated in fear and stress, including the consolidation and extinction of fearful memories, expression profiles of those genes in the brain of suicide victims are les...
FKBP5 is a critical component of the Hypothalamic-Pituitary-Adrenal (HPA) axis, a system which regulates our response to stress. It forms part of a complex of chaperones, which inhibits binding of cortisol and glucocorticoid receptor translocation to the nucleus. Variations in both the HPA axis and FKBP5 have been associated with suicidal behavior. We developed a systematic, targeted sequencing...
Background & Objectives: The rate of suicide varies amongst different parts of Iran. Since there is little knowledge about the risk factors for suicide attempts we carried out this study to determine the status of psychiatric disorders and risk factors of repeated attempted suicide in suicide attempters whom admitted to poisoning emergency in Isfahan, Iran. Methods: Patients with having attempt...
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