Purpose: Ageratum conyzoides is an annual herbaceous plant commonly used in African traditional medicine as a purgative, antipyretic, anti-ulcer and wound dressing agent. The objective of this study was to investigate the acute and sub-chronic toxicity of A. conyzoides leaves in Wistar rats. Methods: In the acute test, the limit test dose of 5000 mg/kg was administered to Wistar rats and then o...

Acute local toxicity refers to the local toxic effects that may result from a single exposure to a chemical or product, by way of the oral, dermal, ocular or inhalation routes. The exposure can be incidental, accidental or deliberate (for example, in the case of cosmetics and certain medicines). The dermal route of exposure can also be a significant route for entry into the systemic circulation...

This study aims to assess the acute and sub-chronic oral toxicity of “Tri 02” powder in experimental animals. According World Health Organization Guidance, was conducted using Swiss mice. LD50 determined by Litchfield-Wilcoxon method, at two doses (2.4 g/kg b.w/day 7.2 b.w/day) assessed Wistar rats for four uninterrupted weeks. Abnormal behavior, toxic symptoms, death were observed 7 consecutiv...

Background: Cadmium is known as a unique heavy metal compared to others, due to its long half-life, low discharge from the body, toxicity at low concentrations and accumulation in tissues. Methods: The effects of chronic and acute Cadmium (Cd) exposure were investigated on the morphology and histopathology of 24 field rats (Millardia meltada). The rats were divided into two groups of 12 each, ...

Silver nanoparticles (AgNPs), owing to their unique physical and chemical properties, have become increasingly popular in consumer products. However, data on their potential biological effects on marine organisms, especially invertebrates, remain very limited. This proof of principle study reports the chronic sub-lethal toxicity of two coated AgNPs (oleic acid coated AgNPs and polyvinylpyrrolid...

All aquatic organisms are directly or indirectly affected by the physical characteristics of their environment, especially the chemical composition of the water. The high concentration levels, damage tissues and interfere with the normal growth and proliferation. The aim of this research was to Investigation acute toxicity of ZnSO4 and CuCl2 to Gambusia holbrooki ...

All aquatic organisms are directly or indirectly affected by the physical characteristics of their environment, especially the chemical composition of the water. The high concentration levels, damage tissues and interfere with the normal growth and proliferation. The aim of this research was to Investigation acute toxicity of ZnSO4 and CuCl2 to Gambusia holbrooki ...

© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Materials and fabrication procedures are described for bioresorbable transistors and simple integrated circuits, in which the key processing steps occur on silicon wafer substrates, in schemes compatible with methods used in conventional microelectronics. The approach relies on an unusual type of silicon on insulator wafer to yield devices that ...

Background & Aims: Dry type localized cutaneous Leishmaniasis due to Leishmania tropica is one of the most prevalent cutaneous parasitic infections in Kerman province. It seems that cellular immune response and the nature of immune inflammatory cells comprising the inflammatory background play a determinant role in this infection. Methods: Skin biopsies of 53 patients with acute(<2 years durati...

Objective: The present investigation was carried out to evaluate the safety of an aqueous extract of the seeds of Calycotome villosa (Poiret) Link (subsp. intermedia) by determining its cytotoxicity and potential toxicity after acute and sub-chronic administration in rodents. Materials and Methods: Cytotoxic activity was tested in cancer and non-cancer cell lines HeLa, Mel-5, HL-60 and 3T3. Acu...