Quantitative structure-activity relationships (QSAR) in the fields of medicinal chemistry, pesticide science, biochemistry and toxicology are being published at an ever increasing rate. In addition to these biological correlation equations, thousands of such equations have been published for all kinds of organic reactions. There is a great need to develop a computerized system to enable one to ...

Most cosmological parameter estimations are based on the same set of observations and are therefore not independent. Here, we test the consistency of parameter estimations using a combination of large-scale structure and supernovae data, without cosmic microwave background (CMB) data. We combine observations from the IRAS 1.2 Jy and Las Campanas redshift surveys, galaxy peculiar velocities and ...

where k = m1 + . . . + mn is the total number of parts, θ > 0 is a parameter of the distribution, and θ = θ(θ + 1) . . . (θ + n − 1). For background and applications to genetics see [11, 12, 13, 6, 5, 19]. This note presents a family of distributions Pn,θ,α for random partitions of n, with two parameters θ ≥ 0 and 0 ≤ α ≤ 1. For α = 0, θ > 0, Pn,θ,0 = Pn,θ as in (1). As indicated at the end of ...

Fuzzy modeling generally comprises structure identification and parameter identification. The former determines the structure of a rule-base, whereas the latter determines the contents of each rule. Applying neural networks or genetic algorithms to identify the parameter sets and structures of a fuzzy system is increasingly popular owing to their ability to learn and adapt. However, most conven...

vinblastine is an important anticancer agent known to diminish microtubule assembly. ab initio calculations are applied to examine the structural properties and different energies of vinblastine-tubulin complex in different dielectric constants and temperatures. the aims of this work are discovery the best optimized structure and thermodynamic properties of vinblastine-tubulin complex and compa...

We consider a variant of the game of Cops and Robbers, called Lazy Cops and Robbers, where at most one cop can move in any round. We investigate the analogue of the cop number for this game, which we call the lazy cop number. Lazy Cops and Robbers was recently introduced by Offner and Ojakian, who provided asymptotic upper and lower bounds on the lazy cop number of the hypercube. By coupling th...

The paper deals with the application of the theory of locally homogeneous and isotropic Gaussian fields (LHIGF) to probabilistic modelling of multivariate data structures. An asymptotic model is also studied, when the correlation function parameter of the Gaussian field tends to infinity. The kriging procedure is developed which presents a simple extrapolator by means of a matrix of degrees of ...

Although it is acknowledged that internal iterators are easier and safer to use than conventional external iterators, it is commonly assumed that they are not applicable in languages without builtin support for closures and that they are less exible than external iterators. We present an iteration framework that uses objects to emulate closures, separates structure exploration and data consumpt...

We give two self-stabilizing algorithms for tree networks. The first computes an index, called guide pair, for each process P in O(h) rounds using O(δP log n) space per process, where h is the height of the tree, δP the degree of P , and n the number of processes in the network. Guide pairs have numerous applications, including ordered traversal or navigation in the tree. Our second algorithm, ...