Purpose – The purpose of this paper is to provide an overview of structural design code development in Mexico, as an example of how code evolution has taken place in many countries, and to discuss the challenges faced in improving code compliance and reducing vulnerability. Design/methodology/approach – All building codes for Mexico City (1920-2004) and current codes in Mexico were analyzed and...

This paper presents a methodology for reducing the uncertainty related to the structural behaviour of an existing building in view of a vulnerability assessment regarding future earthquake actions. Estimating the lateral load resistance is a step towards evaluating the capacity of a structure to resist earthquake actions. The prediction of structural behaviour by numerical models is inevitably ...

SIL1 is a ubiquitous protein of the Endoplasmic Reticulum (ER) acting as a co-chaperone for the ER-resident chaperone, BiP. Recessive mutations of the corresponding gene lead to vulnerability of skeletal muscle and central nervous system in man (Marinesco-Sjögren syndrome; MSS) and mouse. However, it is still unclear how loss of ubiquitous SIL1 leads to selective vulnerability of the nervous sy...

fragility curves represent the probabilities that structural damages, under various levels of seismic excitation, will exceed the specified damage states by means of earthquake intensity damage relations. conceptual aspects related to seismic vulnerability, damage and risk evaluation are discussed first, together with a short review of the most widely used possibilities for the seismic evaluati...

Joint hypermobility is overrepresented among people with anxiety and can be associated with abnormal autonomic reactivity. We tested for associations between regional cerebral grey matter and hypermobility in 72 healthy volunteers using voxel-based morphometry of structural brain scans. Strikingly, bilateral amygdala volume distinguished those with from those without hypermobility. The hypermob...

Discovering the genes that contribute to complex polygenic diseases represents a significant challenge. Investigating the structural genetic variations associated with these disorders may not be sufficiently informative about vulnerability genes modulated by the environment. Characterizing gene expression patterns does not identify the primary differences in gene structure. The convergence of g...

Abstract The seismic vulnerability of public buildings must be estimated using structural or non-structural parameters. Scientists ought to investigate these factors for the estimation and analysis lifelines such as wastewater treatment plants (WWTPs). Although efforts have been made in past, serious operational parameters are not enough defined. This study considers amount shortening supposed ...

Literature has suggested that droughts and societies are mutually shaped and, therefore, both require a better understanding of their coevolution on risk reduction water adaptation. Although the São Paulo Metropolitan Region drew attention because 2013–2015 drought, this was not first event. This paper revisits event 1985–1986 drought to compare evolution management aspects. Documents hydrologi...

As a sustainable means of public transportation, urban rail transit system undergoes rapid expansion in China. How to provide a safe and reliable service has been the subject of growing attention in this context. However, such work is challenging because rail transit systems are quite vulnerable and influenced by a set of interacting factors. Studying these vulnerability factors will contribute...

The predictive value of interpersonal schemas, perfectionism, and thought action-fusion in obsessive-compulsive disorder Objective: Cognitive vulnerability factors are central in the etiology of obsessive-compulsive disorder. Nosological classifications among symptom clusters have been developed to enable the understanding of possible mechanisms underlying obsessive compulsive symptoms. Previou...