Dental biofilms are complex and consists of many different species which can interact with each other and affect virulence properties. In this study we investigated the effect of Parvimonas micra on proteolytic activity in a multi-species bacterial consortium. Multispecies consortia were constructed, with and without P. micra, using the following species: Porphyromonas gingivalis, Prevotella in...

OBJECTIVES To describe the epidemiological, clinical, microbiological characteristics and antimicrobial resistance pattern of Bloodstream infections in Dhahira region, Oman. METHODS Clinical data was collected from all patients with positive blood cultures for two years period. Standard laboratory methods were used for blood culture. Antibiotic sensitivity was tested using Kirby-Bauer disc di...

Streptococcus pyogenes is a significant pathogen of humans, annually causing over 700,000,000 infections and 500,000 deaths. Virulence in S. pyogenes is closely linked to mobile genetic elements like phages and chromosomal islands (CI). S. pyogenes phage-like chromosomal islands (SpyCI) confer a complex mutator phenotype on their host. SpyCI integrate into the 5' end of DNA mismatch repair (MMR...

1. We have produced arthritis in 50 per cent. of the rabbits injected with Streptococcus mitis. 2. The character of the arthritis is identical with that produced by Micrococcus rheumaticus. 3. The exudate in and about the joints partakes of the same nature as that caused by Streptococcus rheumaticus. 4. Bacteriological studies show that Streptococcus mitis can be recovered from about one third ...

OBJECTIVES Streptococcus pyogenes produces extracellular hyaluronidase enzyme. This enzyme is directly associated with the spread of the organism during infection. The objective of the present study was to clone and express the nucleotide sequence of the enzyme which is involved in hyaluronidase enzymatic activity. MATERIALS AND METHODS The enzymatic region of hyaluronidase gene was detected ...

Resistance in streptococci or Gram-negative bacteria is associated with antibiotic consumption. Scarce information exists on the antibiotic susceptibility of bacterial isolates from patients with periodontitis in countries with high antibiotic consumption, as this is an area in which microbiological testing is not performed in daily practice. The present study was undertaken to explore the susc...

BACKGROUND The aim of this longitudinal study was to evaluate the oral microbiota in children from age 3 months to 3 years, and to determine the association of the presence of caries at 3 years of age. METHODS AND FINDINGS Oral biofilms and saliva were sampled from children at 3 months (n = 207) and 3 years (n = 155) of age, and dental caries was scored at 3 years of age. Oral microbiota was ...