Collagen-based scaffolds can be used to mimic the extracellular matrix (ECM) of soft tissues and provide support during tissue regeneration. To better match the native ECM composition and mechanical properties as well as tailor the degradation resistance and available cell binding motifs, other proteins or different collagen types may be added. The present study has explored the use of componen...

ABSTRACT: The brittle fracture of rock is a complicated progressive process caused by isolated microstructural changes. Modelling this process in the compressive stress regime is not straightforward, and precise engineering analysis and design therefore remains problematical. A new way of tackling the problem is through the recently developed local degradation approach, which has been developed...

Herein, we report on the synthesis and characterization of enzymatically labile polyureas for use as a tissue-engineered ligament scaffold. Polyureas were selected due to their excellent tensile properties, fatigue resistance, and highly tunable nature. Incorporation of a collagenase-sensitive peptide into the backbone of the polyurea provided a means to confer cell-responsive degradation to th...

Power transformers use Kraft paper as insulation in the electrical windings present in the core, which is immersed in oil. In service, the temperature of the windings of core will go to 75C to 85C. If the transformer is over loaded, then the temperature can exceed upto 100°C causing the cellulose chains in the paper to cleave at an accelerated rate, which results in the degradation of mechanica...

Profiles of polyribosomes were obtained from etiolated stem segments of Pisum sativum L. var. Alaska isolated in various buffers. Tissue homogenized in a medium containing 0.2 m tris-HCl, pH 8.5, 0.2 m sucrose, 30 mm MgCl(2), and 60 mm KCl yielded polyribosomes exhibiting far less degradation than tissue homogenized in conventional media containing tris-HCl at lower ionic strength and pH. A fur...

In this paper, an adaptive soft handoff algorithm, which dynamically calculates the threshold values for soft handoff based on the received signal strength, is proposed for mobile cellular communication systems. An analytical model is developed to study the performance of soft handoff algorithms. Performance is evaluated in terms of the average number active set updates, the mean size of the ac...

Several studies have investigated self-reinforced polylactic acid (SR-PLA) and polyglycolic acid (SR-PGA) rods which could be used as intramedullary (IM) fixation devices to align and stabilise bone fractures. This study investigated totally bioresorbable composite rods manufactured via compression moulding at ~100 °C using phosphate glass fibres (of composition 50P(2)O(5)-40CaO-5Na(2)O-5Fe(2)O...

Pentachlorophenol (PCP), a highly toxic anthropogenic pesticide, can be mineralized by Sphingobium chlorophenolicum, a gram-negative bacterium isolated from PCP-contaminated soil. However, degradation of PCP is slow and S. chlorophenolicum cannot tolerate high levels of PCP. We have used genome shuffling to improve the degradation of PCP by S. chlorophenolicum. We have obtained several strains ...

Biodegradable implants made from polyglycolic and polylactic acid co-polymers undergo degradation by hydrolysis which results in loss oftheir mechanical strength. The degradation of 1.5 mm polyglycolide rods (Biofix) was studied after intramedullary and subcutaneous implantation in rabbits. Two weeks after implantation there was a 73% reduction in strength of the intramedullary implants and a 6...