Purpose: To investigate the differences in macular and nevre fiber layer thicknesses between amblyopic and fellow eyes. Method: One hundred and twenty two eyes of 61 patients were enrolled for this study. All patients underwent complete ocular examination, cover test, prism test and also RNFL, macular thickness measurements (CMT; central macular thickness, TMT; total macular thickness) were obt...

Persons with amblyopia, especially those with strabismus, are known to exhibit abnormal fixational eye movements. In this paper, we compared six characteristics of fixational eye movements among normal control eyes (n=16), the non-amblyopic fellow eyes and the amblyopic eyes of anisometropic (n=14) and strabismic amblyopes (n=14). These characteristics include the frequency, magnitude of landin...

Amblyopes show specific deficits in processing second-order spatial information (e.g. Wong, Levi, & McGraw (2001). Is second-order spatial loss in amblyopia explained by the loss of first-order spatial input? Vision Research, 41, 2951-2960). Recent work suggests there is a significant degree of plasticity in the visual pathway that processes first-order spatial information in adults with amblyo...

To shed light on the basis of normal contrast perception in general and its susceptibility during early visual development in particular the contrast-coding deficit of amblyopic eyes was investigated. This was accomplished by using two different but complementary paradigms, one involving equating the contrast sensations between the amblyopic and normal fellow eye and the other involving the ass...

Objective: To measure and compare macular thicknesses (MT) in patients that have amblyopia and control group eyes with optical coherence tomography (OCT) and to define OCT as an early diagnosis tool. Methods: 27 patients having amblyopia associated strabismus classified as group 1, 18 patients having amblyopia associated anisometropia classified as group 2 and 45 healthy volunteers classified a...

INTRODUCTION OR BACKGROUND With a prevalence of 2-5%, amblyopia is the most common vision deficit in children in the UK and the second most common cause of functional low vision in children in low-income countries. SOURCES OF DATA Pubmed, Cochrane library and clinical trial registries (clinicaltrials.gov, ISRCTN, UKCRN portfolio database). AREAS OF AGREEMENT Screening and treatment at the a...

Adults with amblyopia were recently shown to perform abnormally in tasks requiring integration of local features into global percepts. Moreover, spatial interactions in amblyopic patients, though often found to be abnormal, showed marked variability. Here we measured collinear lateral interactions using Gabor patches in a large number of amblyopic (N=75) and normal subjects (N=25), testing four...

The notion of a limited, early period of plasticity of the visual system has been challenged by more recent research demonstrating functional enhancement even into adulthood. In amblyopia ("lazy eye") it is still unclear to what extent the reduced effect of treatment after early childhood is due to declining plasticity or lower compliance with prescribed patching. The aim of this study was to d...

PURPOSE Several behavioral studies have shown that the reaction times of visually guided movements are slower in people with amblyopia, particularly during amblyopic eye viewing. Here, we tested the hypothesis that the initiation of smooth pursuit eye movements, which are responsible for accurately keeping moving objects on the fovea, is delayed in people with anisometropic amblyopia. METHODS...