The earliest dissolution apparata included Pernarowski’s basket dissolution assembly2 and Poole’s paddle design.3 Until recently, official dissolution testing methods were based entirely on modifications of these static models. However, these methods suffer from a number of disadvantages4 and the need for a new official dissolution test was recognised, resulting in the introduction of the flow-...

Transient drop-size distributions of stirred dispersions undergoing breakage were experimentally measured at long stining times. The results show that drops continue to break the entire duration of the experiment (at least up to 10 h) and force a reevaluation of the widely held concept of a maximum stable drop diameter, d,,,. Transient distributions show the existence of self-similarity, which ...

Smoluchowski 's coagulation equation with coagulation rates K 0 oc (ij) ~ describing the temporal evaluation of the size distribution ck (concentration of k-mers) is studied in the presence of a source term ark, and a sink term --bCk. With a' a/b 2 one finds that a steady state is reached, exhibiting gelation when w > 1⁄2 and a ' > ao(w), where a0(o~) depends on w (ao(w) = ~ for ~o < 1⁄2, ao(1)...

conclusions alterations were present in both the aspect and spacing of collagen fibrils and in the shape of elastic fibers. the present familial combination of scad and edsh, with almost similar ultrastructural features suggests a possible connection between both conditions. case presentation we present a woman with scad and her five close relatives showing obvious or suggestive signs of edsh. ...

arrhythmogenic right ventricular dysplasia/cardiomyopathy (arvd/c) is a congenital cardiac disease with myocardial involvement, most probably right ventricular (rv) dysfunction, accounting for 20% of sudden cardiac deaths. characterized by the fibro-fatty infiltration of the rv free wall, arvd/c presents in adolescents with ventricular arrhythmias and heart failure symptoms and as biventricular...

purpose : to report a case of congenital macular macrovessels case report : an 8-year-old girl was referred for decreased vision in her right eye. her best corrected visual acuity (bcva) in the right eye was 20/200 and in the left eye 20/20. anterior segment examinations were normal in both eyes. posterior segment examination of the right eye showed abnormal macrovessels crossing the macula and...

This paper presents simulation experiments on the continuous stirred tank reactor (CSTR) which is widely used equipment mainly in the chemical industry. The behaviour of these types of systems is usually nonlinear with other negative properties such as a time-delay or a non-minimum phase behaviour and simulation could help us with the understanding of them without making real experiments which ...

background: differences in the quantity and distribution of coronary veins between patients with ischemic and non-ischemic cardiomyopathy might affect the potential for the left ventricular (lv) lead targeting in patients undergoing cardiac resynchronization therapy (crt). in the current study, we assessed and compared the suitability of the coronary venous system for the lv lead placement in i...