Multiple computational models have been developed to study knee biomechanics. However, the majority of these models are mainly validated against a limited range of loading conditions and/or do not include sufficient details of the critical anatomical structures within the joint. Due to the multifactorial dynamic nature of knee injuries, anatomic finite element (FE) models validated against mult...

During an earthquake, structures are subjected to both horizontal and vertical shaking. Most structures are rather insensitive to variations in the vertical acceleration history and primary considerations are given to the impact of the horizontal shaking on the behavior of structures. In the laboratory, however, most component tests are carried out under uni-directional horizontal loading to si...

in this study, an artificial neural network was developed in order to analyze flexible pavement structure anddetermine its critical responses under the influence of standard axle loading. in doing so, more than 10000four-layered flexible pavement sections composed of asphalt concrete layer, base layer, subbase layer, andsubgrade soil were analyzed under the impact of standard axle loading. pave...

In this paper, the energy absorption features of tri-layer explosive-welded deep-drawn cups subjected to quasi-static axial compressive loading are investigated numerically and experimentally. To produce the cups, tri-layer blanks composed of aluminum and stainless steel alloys were fabricated by an explosive-welding process and formed by a deep drawing setup. The quasi-static tests were carrie...

OBJECTIVE Physiological magnetic resonance imaging (MRI) under loading or knee malalignment conditions has not been thoroughly investigated. We assessed the influence of static loading and knee alignment on T2 (transverse relaxation time) mapping of the knee femoral cartilage of porcine knee joints using a non-metallic pressure device. METHODS Ten porcine knee joints were harvested en bloc wi...

This paper presents an applicable and practical computer program(ODPSAD) and suggests a new algorithm for geometry of concrete arch dams. In this program shape optimization of arch dams for static and dynamic loads and enhancement of its seismic behaviour is carried out. abutment excavation and dam body volumes have been considered as the objective function and in order to increase the consiste...

OBJECTIVES This study investigated removal of a force-closed stem, done in order to improve acetabular exposure during revision, with reinsertion afterwards. It is unknown how much this procedure modifies the stem/cement interface. METHODS Three tapered stem models were implanted into composite femurs. Strain gauges were embedded in the medial aspect of the cement mantle and in several positi...

Although clinical bone fractures occur predominantly under impact loading (as occurs during sporting accidents, falls, high-speed impacts or other catastrophic events), experimentally validated studies on the dynamic fracture behavior of bone, at the loading rates associated with such events, remain limited. In this study, a series of tests were performed on femoral specimens obtained post-mort...

AIM Mechanical forces are important regulators of cell and tissue phenotype. We hypothesized that mechanical loading and boundary conditions would influence neovessel activity during angiogenesis. METHODS AND RESULTS Using an in vitro model of angiogenesis sprouting and a mechanical loading system, we evaluated the effects of boundary conditions and applied loading. The model consisted of rat...