A complete set of harmonic force constants describing the DNA deformation energetics at the base pair level was obtained using unrestrained atomic-resolution molecular dynamics simulations of selected duplex oligonucleotides and subsequent analysis of structural fluctuations from the simulated trajectories. The deformation was described by the six base pair conformational parameters (buckle, pr...

To address the increasing burden of diabetes in New York City, we designed 2 electronic health records (EHRs)-facilitated diabetes management systems to be implemented in 6 primary care practices on the West Side of Manhattan, a standard system and an enhanced system. The standard system includes screening for diabetes. The enhanced system includes screening and ensures close patient follow-up;...

background: there are few studies comparing the biomechanical properties of angled blade plate and locking compression plates in supracondylar osteotomy. in the current randomized study, we prospectively compared the clinical and radiological outcomes of supracondylar osteotomy using these two plates. methods: forty patients with valgus knee malalignment were randomly assigned to two equal numb...

glutathione s-transferases (gsts) are members of multigenic family which have the essential functionin cells as an antioxidant. in the present study we studied the polymorphism of gstt1 and gstm1 deletion genotypes in iranian patients with primary closed angle glaucoma (pcag) compared to healthy subjects. we conducted a study of 41 pcag patients (24 women, 17 men) and 100 healthy participants (...

As a major driving force to improve economic output, commercial blocks also play significant role in enhancing urban vitality. Due its characteristics of high building density and large volume, many wind environment problems are likely appear blocks. In this research, we simulated the four theoretical block models real STREAM software. The results suggest that under same other conditions, speed...

We propose a pattern projection method for one-shot active 3D shape measurement to reconstruct movable or deformable scenes. In our method, just one projection pattern which has scene slant-invariant features is used to solve the correspondence between camera and projector pixel coordinates. Additionally, in order to correct correspondence in complex scenes which include discontinuous and overl...

objectives: patellar maltracking is the main reason for pain and disability in patellofemoral pain syndrome (pfps). patellar taping can considerably reduce such pain and disability. this study compared the effectiveness of physiotherapy exercises and kinesio taping on the patellar position in women with pfps (mean age 32.2±1.12 years) by using magnetic resonance imaging (mri). methods: thirty w...

purpose : to compare the serum homocysteine (hcy) level in healthy control individuals and in patient with primary open angle glaucoma (poag) and pseudoexfoliative glaucoma (pexg) methods : in this cross sectional study, 79 subjects including 36 patients with pexg, 23 patients with poag, and 20 matched healthy control individuals were recruited. those who used alcohol and mediations affecting h...