INTRODUCTION Our aim is to evaluate the influence of clinical and histopathological parameters, including age, gender, tumor stage, grade, tumor differentiation, necrosis, lymphovascular/perineural invasion (LVI/PNI) and concomitant carcinoma in situ (CIS), on outcomes of patients with urothelial carcinoma of the bladder (UCB). MATERIAL AND METHODS A total of 84 patients who underwent radical...

This study describes the chemical composition of the essential oil of Artemisia maritima (Am.Oil) and the pharmacological basis for its medicinal use in gut and airways disorders. Twenty five compounds, composing 93.7% of the oil, were identified; among these, chrysanthenyl propionate and elixene were identified for the first time from any Artemisia species. The Am.Oil (0.3-1.0 mg/mL) suppresse...

Introduction It has been shown that CD47 is an important diagnostic and prognostic marker in many cancer types. However, the relationship between CD47 and bladder tumor stage has not been shown in previous studies. To the best of our knowledge, this is the first study investigating the association of CD47 with stages of bladder cancer. Material and methods Surgical specimens of 175 patients w...

Cracks are a major sign of aging transportation infrastructure. The detection and repair cracks is the key to ensuring overall safety In recent years, due remarkable success deep learning (DL) in field crack detection, many researches have been devoted developing pixel-level image segmentation (CIS) models based on DL improve accuracy, but as far we know there no review DL-based CIS methods yet...

Background and objectives: The genus Verbascum, with nearly 360 species, is one of the largest members of Schrophulariacea family. In the Flora of Iran, the genus Verbascum is represented by 43 species among them seventeen plants are endemic. Verbascum species are well known in folk medicine and are widely used for therapeutic purposes. Verbascum sublobatum Murb. grows wildly in north of Iran. ...

The synthesis of the title compound is described. Deprotection of Cis(N-Trityl-3-azido-4-Styryl)-2-azetidinone to Cis-(3-azido-4-styryl)-2-azetidinone was found to be accelerated by the special salt effect under acidic condition

We present OSFormer, the first one-stage transformer framework for camouflaged instance segmentation (CIS). OSFormer is based on two key designs. First, we design a location-sensing (LST) to obtain location label and instance-aware parameters by introducing location-guided queries blend-convolution feed-forward network. Second, develop coarse-to-fine fusion (CFF) merge diverse context informati...

Platinum-based anticancer drugs are chemotherapeutic agents to treat cancer. Carboplatin (cis diammine cyclobutane dicarboxylate platinum (II)) is a second generation drug that has less toxic than cisplatin, allowing for high dosages. In the first stage, 1,3-Cyclobutane dicarboxylic acid, a key intermediate for the preparation of carboplatin, have been synthesized in good yields using diffe...