Multiple methods and materials are available for bone defect reconstruction. Bone graft substitute is one of the materials used for reconstruction of bone defect and have been widely used recently. This report describes some cases about complications related to GeneX® which is introduced as mixture of calcium sulfate and β-tricalcium phosphate at manufacturer's official web site. It informed of...

PURPOSE Implant beds with an insufficient amount of cortical bone or a loss of cortical bone can result in the initial instability of a dental implant. Thus, the objective of this study was to evaluate the effect of bone cement grafting on implant initial stability in areas with insufficient cortical bone. METHODS Two different circumferential defect depths (2.5 mm and 5 mm) and a control (no...

Foraminifera carbonate exoskeleton was hydrothermally converted to biocompatible and biodegradable zinc-tricalcium phosphate (Zn-TCP) as an alternative biomimetic material for bone fracture repair. Zn-TCP samples implanted in a rat tibial defect model for eight weeks were compared with unfilled defect and beta-tricalcium phosphate showing accelerated bone regeneration compared with the control ...

While free flaps have been widely used for reconstruction of pretibial defects, the extended operation times are known to be a major drawback. This report presents case successful lower leg large defect with bone-anchored advancement flap and split-thickness skin graft. A 59-year-old female patient underwent wide excision sarcoma on area. The measured 14×6 cm 10×2 exposure tibia in medial aspec...

Bone fracture healing is a complex process including inflammation, repair and remodeling. Bone grafts or substitute are widely accepted to treat impaired healing. Newly developed bone substitutes must undergo in vitro and in vivo testing before clinical application. All kinds of intraosseous and heterotopic implant models in small and/ or large animals are used for different bone substitutes. O...

Objective: This study describes the bone transportation technique for partial bone defect, and shows clinical and radiological results of a series of patients treated by using this method. Material and Methods: Nine patients with partial bone defect were treated (six tibia and three femur). Every patient had infection and nonunion. The initial procedure was to stabilize the bone, followed by a ...

Bionic modeling technology of bone defect repair plays a key role in the process of repairing defective bone based on tissue engineering. In this paper, via studying the structure of bone defect repair, new concept of bionic scaffold is put forward and a new method of integrating medical image processing, 3D reconstruction and CAD technology to construct the bionic scaffold of repairing bone de...

BACKGROUND Extended Soft tissue defect of leg including middle and distal parts always has been a challenge for many plastic surgeons and also a frustrated problem for patients and families. To introduce the use of the soleus muscle and reverse sural flaps as synchronous surgical treatment alternative of the leg bone exposure with large soft tissue defect, this study was conducted. METHODS T...

Objective- The aim of this study was to evaluate possible beneficial effect of tricalcium phosphate/collagen (TCP/collagene) nanocomposite scaffold on bone healing in rabbits using biochemical assessmentsDesign- Experimental studyAnimals- Twelve healthy male white New Zealand rabbitsProcedures- The rabbits wer...

Fig. 1. Schematic of one stage bone transport procedure (yellow bone, red periosteum). A portion of diaphyseal bone is denuded of periosteum, osteotomized, and transported over an intramedullary nail to the site of the 2.54-cm critical-sized defect, where it is docked to the distal femur. The periosteal sheath is left in situ to surround the new defect site, leading to full infilling of the new...